Evidence map›Paper›PMID 34916189›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

[Regulatory mechanism of interferon regulatory factor 1 by

F Mu, X Chen, X DU, Q Jiao, M Bi, H Jiang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

F MuState Key Disciplines of Physiology (Incubation), Department of Physiology, Qingdao University, Qingdao 266071, China.
X ChenState Key Disciplines of Physiology (Incubation), Department of Physiology, Qingdao University, Qingdao 266071, China.
X DUState Key Disciplines of Physiology (Incubation), Department of Physiology, Qingdao University, Qingdao 266071, China.
Q JiaoState Key Disciplines of Physiology (Incubation), Department of Physiology, Qingdao University, Qingdao 266071, China.
M BiState Key Disciplines of Physiology (Incubation), Department of Physiology, Qingdao University, Qingdao 266071, China.
H JiangState Key Disciplines of Physiology (Incubation), Department of Physiology, Qingdao University, Qingdao 266071, China.
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the molecular mechanism by which

methodsSH-SY5Y cells overexpressing

results

conclusion

Indexed as

alpha-SynucleinParkinson DiseaseAnimalsInterferon Regulatory Factor-1MiceMice, TransgenicProto-Oncogene Proteins c-mdm2Ubiquitinationalpha-SynucleinInterferon Regulatory Factor-1Irf1 protein, mouseMdm2 protein, mouseProto-Oncogene Proteins c-mdm2interferon regulatory factor 1neuroimmuneParkinson's diseaseα-synuclein

Identifiers

PMID34916189
PMCPMC8685704
OpenAlexW4200530891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.