Evidence map›Paper›PMID 34916185›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

[Renal sympathetic denervation can significantly reduce blood pressure and improve arterial stiffness in hypertensive beagles].

F Ye, G Shi, X Wang, S Tu, Z Zhang, L Zeng

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

F YeDepartment of Cardiology, Third Xiangya Hospital of Central South University, Changsha 410013, China.
G ShiInternal Medicine, Changsha Health Vocational College, Changsha 410013, China.
X WangDepartment of Cardiology, Third Xiangya Hospital of Central South University, Changsha 410013, China.
S TuDepartment of Cardiology, Third Xiangya Hospital of Central South University, Changsha 410013, China.
Z ZhangDepartment of Cardiology, Third Xiangya Hospital of Central South University, Changsha 410013, China.
L ZengDepartment of Cardiology, Third Xiangya Hospital of Central South University, Changsha 410013, China.
Central South University · CNChangsha University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of renal sympathetic denervation (RDN) on blood pressure and arterial stiffness in hypertensive beagles and explore the underlying mechanism.

methodsSixteen beagles were randomly divided into RDN group (

resultsAll the animal models of hypertension were established successfully in the beagles. At 3 months after the RDN, the changes in systolic blood pressure (SBP) differed significantly among the 3 groups (

conclusionRDN can significantly reduce blood pressure and improve arterial stiffness in hypertensive beagles possibly by reducing sympathetic activity and blood pressure and promoting NO synthesis.

Indexed as

HypertensionHypotensionVascular StiffnessAnimalsBlood PressureDogsSympathectomyarterial stiffnesshypertensionrenal sympathetic denervationsympathetic activity

Identifiers

PMID34916185
PMCPMC8685710
OpenAlexW4200368095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.