Evidence map›Paper›PMID 34915944›Full record

ArticlePublic health nutrition2023

Community-based management of acute malnutrition for infants under 6 months of age is safe and effective: analysis of operational data.

Maeve M Woeltje, Anastasia B Evanoff, Beth A Helmink, Diana L Culbertson, Kenneth M Maleta, Mark J Manary, Indi Trehan

Open access · hybridAbstract read
In one paragraph

Article in Public health nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Maeve M WoeltjeDepartment of Pediatrics, University of Washington, 4800 Sand Point Way NE, M/S MB.7.520, Seattle, WA98105, USA.
Anastasia B EvanoffDepartment of Psychiatry, Harvard University, Boston, USA.
Beth A HelminkDepartment of Surgery, Washington University in St. Louis, St Louis, USA.
Diana L CulbertsonSeattle Children's Hospital, Seattle, USA.
Kenneth M MaletaSchool of Public Health and Family Medicine, Kamuzu University of Health Sciences, Blantyre, Malawi.ORCID 0000-0002-2536-3938
Mark J ManarySchool of Public Health and Family Medicine, Kamuzu University of Health Sciences, Blantyre, Malawi.
Indi TrehanDepartment of Pediatrics, University of Washington, 4800 Sand Point Way NE, M/S MB.7.520, Seattle, WA98105, USA.ORCID 0000-0002-3364-6858
Seattle Children's Hospital · USWashington University in St. Louis · USBoston University · USKamuzu Central Hospital · MW

Funding

Training of the Pediatric Emergency Physician-ScientistT32HD049338 · NICHD · WASHINGTON UNIVERSITY · PI SCHNADOWER, DAVID · 2007 to 2016
$1.3M
NICHD NIH HHS T32 HD049338
6 · The paper itself

Abstract

objectiveTo assess the effectiveness of outpatient management with ready-to-use and supplementary foods for infants under 6 months (u6m) of age who were unable to be treated as inpatients due to social and economic barriers.

designReview of operational acute malnutrition treatment records.

settingTwenty-one outpatient therapeutic feeding clinics in rural Malawi.

participantsInfants u6m with acute malnutrition treated as outpatients because of barriers to inpatient treatment. The comparison group consisted of acutely malnourished children 6-9 months of age who were being treated at the same time in the same location in the context of two different randomised clinical trials.

resultsA total of 323 infants u6m were treated for acute malnutrition (130 severe and 193 moderate). A total of 357 infants 6-9 months old with acute malnutrition (seventy-four severe and 283 moderate) were included as contemporaneous controls. Among infants u6m with severe acute malnutrition, 98 (75·4 %) achieved nutritional recovery; in comparison, 56 (75·7 %) of those with severe acute malnutrition 6-9 months old recovered. Among infants u6m with moderate acute malnutrition, 157 (81·3 %) recovered; in comparison, 241 (85·2 %) of those aged 6-9 months recovered.

conclusionsIn a rural Malawian population of infants u6m who had generally already stopped exclusive breast-feeding and were now acutely malnourished, treatment with therapeutic or supplementary foods under the community management of acute malnutrition model was safe and effective. In settings where social and financial factors make hospital admission challenging, consideration should be given to lowering the recommended age of ready-to-use therapeutic and supplementary foods to infants u6m.

Indexed as

MalnutritionSevere Acute MalnutritionBreast FeedingChildFemaleHospitalizationHumansInfantMalawiKwashiorkorMarasmusModerate acute malnutritionReady-to-use supplementary foodReady-to-use therapeutic foodSevere acute malnutritionWasting

Identifiers

PMID34915944
PMCPMC11077441
OpenAlexW4200488317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.