Evidence map›Paper›PMID 34915750›Full record

ArticleThyroid : official journal of the American Thyroid Association2022

Pathogenesis of Multinodular Goiter in Elderly XB130-Deficient Mice: Alteration of Thyroperoxidase Affinity with Iodide and Hydrogen Peroxide.

Hae-Ra Cho, Junichi Sugihara, Hiroki Shimizu, Yun-Yan Xiang, Xiaohui Bai, Yingchun Wang, Xiao-Hui Liao, Sylvia L Asa, Samuel Refetoff, Mingyao Liu

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Hae-Ra ChoLatner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
Junichi SugiharaLatner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
Hiroki ShimizuLatner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.ORCID 0000-0002-6463-8498
Yun-Yan XiangLatner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
Xiaohui BaiLatner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
Yingchun WangLatner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
Xiao-Hui LiaoDepartment of Medicine, The University of Chicago, Chicago, Illinois, USA.
Sylvia L AsaDepartment of Pathology, University Health Network, Toronto, Canada.ORCID 0000-0001-8418-5054
Samuel RefetoffDepartment of Medicine, The University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-0164-8231
Mingyao LiuLatner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.ORCID 0000-0002-9188-8417
University Health Network · CAUniversity of Chicago · US

Funding

THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERSR01DK015070 · NIDDK · UNIVERSITY OF CHICAGO · PI ANTONIO C BIANCO, Alexandra Mihaela Dumitrescu · 1986 to 2026
$8.1M
CIHR MOP-119514CIHR MOP-13270CIHR MOP-42546NIDDK NIH HHS R01 DK015070
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Congenital HypothyroidismGoiterAgedAnimalsFemaleHumansHydrogen PeroxideIodide PeroxidaseIodidesMaleMiceThyroid HormonesHydrogen PeroxideIodide PeroxidaseIodidesThyroid Hormonesadaptor proteinagingcytoskeletonhypothyroidismiodide organification

Identifiers

PMID34915750
PMCPMC9048175
OpenAlexW4200026004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.