Evidence map›Paper›PMID 34915558›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022

Associations Between Changes in Loneliness and Social Connections, and Mental Health During the COVID-19 Pandemic: The Women's Health Initiative.

Joseph S Goveas, Roberta M Ray, Nancy F Woods, JoAnn E Manson, Candyce H Kroenke, Yvonne L Michael, Aladdin H Shadyab, Jaymie R Meliker, Jiu-Chiuan Chen, Lisa Johnson and 7 more

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
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  8. Investigating Biological Pathways Underpinning the Longitudinal Association Between Loneliness and Cognitive Impairment.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  9. Changes in Fall Rates From Before to During the COVID-19 Pandemic: Findings From the Prospective AMBROSIA Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  10. What We've Learned From the Women's Health Initiative Participants About Their COVID-19 Experience.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Joseph S GoveasDepartment of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Roberta M RayFred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Nancy F WoodsUniversity of Washington School of Nursing, Seattle, Washington, USA.ORCID 0000-0001-8396-3467
JoAnn E MansonDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Candyce H KroenkeDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Yvonne L MichaelDepartment of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, Pennsylvania, USA.
Aladdin H ShadyabHerbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, California, USA.
Jaymie R MelikerProgram in Public Health, Department of Family, Population and Preventive Medicine, Stony Brook University, Stony Brook, New York, USA.
Jiu-Chiuan ChenDepartments of Preventive Medicine and Neurology, University of Southern California Keck School of Medicine, Los Angeles, California, USA.
Lisa JohnsonFred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Charles MoutonOffice of the Provost, University of Texas Medical Branch, Galveston, Texas, USA.
Nazmus SaquibCollege of Medicine, Sulaiman AlRajhi University, Al Bukayriyah, Saudi Arabia.ORCID 0000-0002-2819-2839
Julie WeitlaufVeterans Affairs Palo Alto Health Care System, Palo Alto, California, USA.
Jean Wactawski-WendeDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo (SUNY), Buffalo, New York, USA.ORCID 0000-0003-3096-9595
Michelle NaughtonOhio State University College of Medicine, Columbus, Ohio, USA.
Sally ShumakerDepartment of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Garnet L AndersonFred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Funding

WOMEN'S HEALTH INITIATIVE - CLINICAL COORDINATING CENTER: TASK AREA B - LONG LIFE STUDY VISIT 2 LIMITED HOME VISIT75N92021D00001 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ANDERSON, GARNET L. · 2021 to 2025
$52.0M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A275N92021D00002 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WACTAWSKI-WENDE, JEAN · 2021 to 2025
$6.9M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00004 · NHLBI · STANFORD UNIVERSITY · PI STEFANICK, MARCIA · 2021 to 2025
$6.5M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00003 · NHLBI · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA · 2021 to 2025
$5.0M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00005 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI VITOLINS, MARA · 2021 to 2025
$4.2M
Social networks and disparities in health behaviors and breast cancer outcomes in immigrant womenR01CA230440 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KROENKE, CANDYCE H · 2019 to 2024
$3.2M
An Electronic Health Record-Based Tool to Identify Newly Diagnosed Breast Cancer Patients at Risk of Low Social SupportR01CA253028 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KROENKE, CANDYCE H · 2020 to 2025
$2.6M
Emotion Regulation in Complicated GriefR01MH122490 · NIMH · MEDICAL COLLEGE OF WISCONSIN · PI GOVEAS, JOSEPH S · 2020 to 2024
$2.6M
Endocannabinoid System and Brain Network Function in Late-Life DepressionR21MH109807 · NIMH · MEDICAL COLLEGE OF WISCONSIN · PI GOVEAS, JOSEPH S, HILLARD, CECILIA J · 2017 to 2018
$424k
NCI NIH HHS R01 CA230440NCI NIH HHS R01 CA253028NHLBI NIH HHS 75N92021D00001NHLBI NIH HHS 75N92021D00002NIH HHS R01 MH122490NIMH NIH HHS R01 MH122490NIMH NIH HHS R21 MH109807WHI NIH HHS 75N92021D00003WHI NIH HHS 75N92021D00004WHI NIH HHS 75N92021D00005
6 · The paper itself

Abstract

backgroundOlder women have faced significant disruptions in social connections during the coronavirus disease 2019 pandemic. Whether loneliness increased or whether a change in loneliness from pre- to intrapandemic period was associated with mental health during the pandemic is unknown.

methodsOlder women (n = 27 479; mean age 83.2 [SD: 5.4] years) completed surveys in mid-2020, including questions about loneliness, living arrangements, changes in social connections, and mental health. Loneliness was also previously assessed in 2014-2016. We examined whether loneliness changed from the pre- to intrapandemic period and explored factors associated with this change. In multivariable models, we investigated the association of changes in loneliness and social connections with mental health.

resultsLoneliness increased from pre- to intrapandemic levels. Factors associated with worsening loneliness included older age, experiencing stressful life events, bereavement, histories of vascular disease and depression, and social connection disruptions. Factors associated with a decrease in loneliness included identifying as Black, engaging in more frequent physical activity, being optimistic, and having a higher purpose in life. A 3-point increase in loneliness scores was associated with higher perceived stress, higher depressive, and higher anxiety symptoms. Social connection disruptions showed modest or no associations with mental health.

conclusionsLoneliness increased during the pandemic in older women and was associated with higher stress, depressive, and anxiety symptoms. Our findings point to opportunities for interventions targeting lifestyle behaviors, well-being, disrupted social connections, and paying closer attention to those with specific medical and mental health histories that may reduce loneliness and improve mental health.

Indexed as

COVID-19AgedAged, 80 and overAnxietyDepressionFemaleHumansLonelinessMental HealthPandemicsSARS-CoV-2Women's HealthAnxietyDepressionLonelinessSARS-CoV-2Social connectionStressWomen

Identifiers

PMID34915558
PMCPMC8754805

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.