Evidence map›Paper›PMID 34915509›Full record

ArticleDigestive surgery2022

Surgery in Autoimmune Pancreatitis.

Sara Nikolic, Poya Ghorbani, Raffaella Pozzi Mucelli, Sam Ghazi, Francisco Baldaque-Silva, Marco Del Chiaro, Ernesto Sparrelid, Caroline S Verbeke, J-Matthias Löhr, Miroslav Vujasinovic

Abstract read
In one paragraph

Article in Digestive surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients.United European gastroenterology journal · 2025
    Article
  4. Risk of Pancreatic Cancer in Inflammatory Pancreatic Diseases.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sara NikolicDepartment of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.
Poya GhorbaniDepartment of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Raffaella Pozzi MucelliDepartment of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Sam GhaziDepartment of Pathology, Karolinska University Hospital, Stockholm, Sweden.
Francisco Baldaque-SilvaDepartment of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.
Marco Del ChiaroDepartment of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Ernesto SparrelidDepartment of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Caroline S VerbekeDepartment of Pathology, Karolinska University Hospital, Stockholm, Sweden.
J-Matthias LöhrDepartment of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Miroslav VujasinovicDepartment of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAutoimmune pancreatitis (AIP) is a disease that may mimic malignant pancreatic lesions both in terms of symptomatology and imaging appearance. The aim of the present study is to analyze experiences of surgery in patients with AIP in one of the largest European cohorts. PATIENTS AND

methodsWe performed a single-center retrospective study of patients diagnosed with AIP at the Department of Abdominal Diseases at Karolinska University Hospital in Stockholm, Sweden, between January 2001 and October 2020.

resultsThere were 159 patients diagnosed with AIP, and among them, 35 (22.0%) patients had surgery: 20 (57.1%) males and 15 (42.9%) females; median age at surgery was 59 years (range 37-81). Median follow-up period after surgery was 50 months (range 1-235). AIP type 1 was diagnosed in 28 (80%) patients and AIP type 2 in 7 (20%) patients. Malignant and premalignant lesions were diagnosed in 8 (22.9%) patients for whom AIP was not the primary differential diagnosis, but in all cases, it was described as a simultaneous finding and recorded in retrospective analysis in histological reports of surgical specimens.

conclusionsDiagnosis of AIP is not always straightforward, and in some cases, it is not easy to differentiate it from the malignancy. Surgery is generally not indicated for AIP but might be considered in patients when suspicion of malignant/premalignant lesions cannot be excluded after complete diagnostic workup.

Indexed as

Autoimmune DiseasesAutoimmune PancreatitisPancreatic NeoplasmsPancreatitisAdultAgedAged, 80 and overDiagnosis, DifferentialFemaleHumansMaleMiddle AgedPancreasRetrospective StudiesAutoimmune pancreatitisIgG4Pancreatic cancerSurgery

Identifiers

PMID34915509
PMCPMC8985041

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.