Evidence map›Paper›PMID 34915403›Full record

ArticleGait & posture2022

Increased foot strike variability during turning in Parkinson's disease patients with freezing of gait.

Lakshmi Pillai, Kunal Shah, Aliyah Glover, Tuhin Virmani

Abstract read
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Article in Gait & posture, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Lakshmi PillaiDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Kunal ShahDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Aliyah GloverDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Tuhin VirmaniDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Center for Translational Neuroscience, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address: TVirmani@uams.edu.

Funding

Telemedicine CoreP30GM110702 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI GARCIA-RILL, EDGAR E. · 2014 to 2018
$6.1M
NIGMS NIH HHS P30 GM110702
6 · The paper itself

Abstract

backgroundTurning is a common trigger for freezing episodes in patients with Parkinson's disease (PD). Freezing during turning can lead to falls and fractures and decreased quality of life. RESEARCH QUESTION: Does foot-strike contact variability also increase during turning, as previously reported in straight gait in PD patients with Freezing of Gait (FOG)?

methodsSubjects were instructed to walk on a gait mat, making "normal pivot" (180°) turns at each end. ProtoKinetics Movement Analysis Software (PKMAS) software was used for analysis. Video recordings and foot-pressure-prints were studied to identify and define turn segments. Spatiotemporal gait and turn measures were then determined only for the turn segments. A movement disorders neurologist determined clinical freezes.

results100 subjects (28 controls, 38 noFOG and 34 FOG) were included. Compared to non-freezers (noFOG), FOG subjects had a smaller foot-strike during turning (a measure of completeness of foot contact with the mat) and increased foot-strike variability. FOG subjects also had a shorter stride-length, slower stride-velocity, and greater swing phase time and percentage during turns. After adjusting for turn direction, inner/outer leg dynamics showed heavier inner leg footsteps in FOG subjects. 38% of FOG subjects experienced freezes during turning. 69% of freezes occurred during the middle third of the turn. Turn-freezers had more severe spatiotemporal gait deficits. SIGNIFICANCE: Developing targeted therapies to retrain subjects to plant their whole foot on the ground with more consistency could help decrease episodes of freezing of gait.

Indexed as

Gait Disorders, NeurologicParkinson DiseaseGaitHumansQuality of LifeWalkingFallsFreezing of gaitGait quantificationParkinson’s diseaseTurning

Identifiers

PMID34915403
PMCPMC9109154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.