Evidence map›Paper›PMID 34915192›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2022

FTO promotes multiple myeloma progression by posttranscriptional activation of HSF1 in an m

Aoshuang Xu, Jiasi Zhang, Liping Zuo, Han Yan, Lei Chen, Fei Zhao, Fengjuan Fan, Jian Xu, Bo Zhang, Yuyang Zhang and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 83 citations in OpenAlex.

  1. FTO-mediated mRNA biology · 2026
    Article
  2. NChemical biology & drug design · 2026
    Article
  3. Article
  4. Review
  5. PRRC2A-mediated mCell death & disease · 2026
    Article
  6. Article
  7. Emerging roles of RNA mInternational journal of oncology · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. FTO-dependent mInflammation · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. NSUN2-mediated RNA mScientific reports · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Aoshuang XuInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Jiasi ZhangInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Liping ZuoInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Han YanInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Lei ChenInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Fei ZhaoInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Fengjuan FanInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Jian XuInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Bo ZhangInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Yuyang ZhangInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Xuejiao YinInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Qianwen ChengInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Su GaoInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Jun DengInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Heng MeiInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhiping HuangDepartment of Hematology, Jingzhou Central Hospital, Jingzhou 434020, China.
Chunyan SunInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: suncy0618@163.com.
Yu HuInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: dr_huyu@126.com.
Union Hospital · CNJingzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N

Indexed as

Alpha-Ketoglutarate-Dependent Dioxygenase FTOMultiple MyelomaAdenosineAnimalsHeat Shock Transcription FactorsHumansMiceMice, Inbred NODRNA-Binding ProteinsRNA, MessengerAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanFTO protein, mouseHeat Shock Transcription FactorsHsf1 protein, mouseRNA-Binding ProteinsRNA, MessengerYTHDF2 protein, humanFTOHSF1m(6)A methylationmetastasismultiple myeloma

Identifiers

PMID34915192
PMCPMC8899603
OpenAlexW4200417088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.