Evidence map›Paper›PMID 34914845›Full record

Trial reportCancer2022

The Survivorship Sleep Program (SSP): A synchronous, virtual cognitive behavioral therapy for insomnia pilot program among cancer survivors.

Daniel L Hall, Kimberly A Arditte Hall, Mark J Gorman, Amy Comander, Michael R Goldstein, Tony J Cunningham, Sarah Wieman, Helen R Mizrach, Brooke C Juhel, Raissa Li and 3 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04566068 (Adapted Telehealth Intervention for Insomnia Among Cancer Survivors), which is not on this map. Cited by 13 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 5 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04566068 nacompletednot on this map

Adapted Telehealth Intervention for Insomnia Among Cancer Survivors

TypeinterventionalSponsorMassachusetts General HospitalRan2020 to 2021Enrolled40ConditionsCancer, InsomniaArmsIntervention- Adapted Virtual Insomnia Program, Control- Enhanced usual care
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Cancer survivors' acceptability and perspectives on engagement with digital cognitive-behavioral therapy for insomnia: a mixed methods perspective.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  11. Article
  12. Living Your Best Life: Lifestyle Medicine for All Women.American journal of lifestyle medicine
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Daniel L HallDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0002-4069-5324
Kimberly A Arditte HallDepartment of Psychology and Philosophy, Framingham State University, Framingham, Massachusetts.
Mark J GormanDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Amy ComanderHarvard Medical School, Boston, Massachusetts.
Michael R GoldsteinHarvard Medical School, Boston, Massachusetts.
Tony J CunninghamHarvard Medical School, Boston, Massachusetts.
Sarah WiemanDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Helen R MizrachHarvard Medical School, Boston, Massachusetts.
Brooke C JuhelHarvard Medical School, Boston, Massachusetts.
Raissa LiHarvard Medical School, Boston, Massachusetts.ORCID 0000-0003-4929-9739
Alexandros MarkowitzHarvard Medical School, Boston, Massachusetts.
Michael GrandnerDepartment of Psychiatry, The University of Arizona, Tucson, Arizona.
Elyse R ParkDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0002-6319-264X
Harvard University · USBeth Israel Deaconess Medical Center · USBoston College · USFramingham State University · USUniversity of Arizona · US

Funding

TRAINING IN SLEEP, CIRCADIAN &RESPIRATORY NEUROBIOLOGYT32HL007901 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Charles A Czeisler · 1998 to 2026
$18.5M
Examining Delivery of Integrated Tobacco Treatment in Cancer CareK24CA197382 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PARK, ELYSE R. · 2015 to 2019
$841k
A Multimodal Mind-Body Intervention for Fear of Recurrence among Cancer SurvivorsK23AT010157 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI HALL, DANIEL LEE · 2019 to 2023
$785k
American Cancer SocietyNCCIH NIH HHS K23 AT010157NCI NIH HHS K24 CA197382NHLBI NIH HHS T32 HL007901
6 · The paper itself

Abstract

backgroundFor cancer survivors, insomnia is prevalent, distressing, and persists for years if unmanaged. Cognitive behavioral therapy for insomnia (CBT-I) is an effective treatment yet can be difficult to access and may require modification to address survivorship-specific barriers to sleep. In this 2-phase study, the authors adapted and assessed the feasibility, acceptability, and preliminary effects of synchronous, virtual CBT-I adapted for cancer survivors (the Survivorship Sleep Program [SSP]).

methodsFrom April to August 2020, cancer survivors with insomnia (N = 10) were interviewed to refine SSP content and delivery. From October 2020 to March 2021, 40 survivors were recruited for a randomized controlled trial comparing 4 weekly SSP sessions with enhanced usual care (EUC) (CBT-I referral plus a sleep hygiene handout). Feasibility and acceptability were assessed by enrollment, retention, attendance, fidelity, survey ratings, and exit interviews. Insomnia severity (secondary outcome), sleep quality, sleep diaries, and fatigue were assessed at baseline, postintervention, and at 1-month follow-up using linear mixed models.

resultsThe SSP included targeted content and clinician-led, virtual delivery to enhance patient centeredness and access. Benchmarks were met for enrollment (56% enrolled/eligible), retention (SSP, 90%; EUC, 95%), attendance (100%), and fidelity (95%). Compared with EUC, the SSP resulted in large, clinically significant improvements in insomnia severity (Cohen d = 1.19) that were sustained at 1-month follow-up (Cohen d = 1.27). Improvements were observed for all other sleep metrics except sleep diary total sleep time and fatigue.

conclusionsSynchronous, virtually delivered CBT-I targeted to cancer survivors is feasible, acceptable, and seems to be efficacious for reducing insomnia severity. Further testing in larger and more diverse samples is warranted.

Indexed as

Cancer SurvivorsCognitive Behavioral TherapyNeoplasmsSleep Initiation and Maintenance DisordersHumansPilot ProjectsSleepSurvivorshipTreatment Outcomecancerinsomniarandomized controlled trialsurvivorshipvirtual interventions

Identifiers

PMID34914845
PMCPMC8917089
OpenAlexW4200127181

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.