Evidence map›Paper›PMID 34914673›Full record

ArticleMMWR. Morbidity and mortality weekly report2021

Trends in and Characteristics of Drug Overdose Deaths Involving Illicitly Manufactured Fentanyls - United States, 2019-2020.

Julie O'Donnell, Lauren J Tanz, R Matt Gladden, Nicole L Davis, Jessica Bitting

Open access · diamondAbstract read
In one paragraph

Article in MMWR. Morbidity and mortality weekly report, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 1 pooled it
36.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 1 synthesis or guideline pooled it, 229 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Socioenvironmental disasters and the dialectics of overdose mortality.The International journal on drug policy · 2026
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  7. Nondual Awareness as a Novel Chronic Pain Relieving Mechanism.Psychology of consciousness (Washington, D.C.) · 2026
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  15. The Toxicology Investigators Consortium 2024 Annual Report.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
    Article
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  19. Naloxone Disparities in Adolescents: Access Laws Are Not Enough.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  20. Article

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julie O'Donnell
Lauren J Tanz
R Matt Gladden
Nicole L Davis
Jessica Bitting

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During May 2020-April 2021, the estimated number of drug overdose deaths in the United States exceeded 100,000 over a 12-month period for the first time, with 64.0% of deaths involving synthetic opioids other than methadone (mainly illicitly manufactured fentanyls [IMFs], which include both fentanyl and illicit fentanyl analogs).* Introduced primarily as adulterants in or replacements for white powder heroin east of the Mississippi River (1), IMFs are now widespread in white powder heroin markets, increasingly pressed into counterfeit pills resembling oxycodone, alprazolam, or other prescription drugs, and are expanding into new markets, including in the western United States

Indexed as

AdolescentAdultAgedDrug OverdoseFemaleFentanylHumansIllicit DrugsMaleMiddle AgedUnited StatesYoung AdultFentanylIllicit Drugs

Identifiers

PMID34914673
PMCPMC8675656
OpenAlexW4200272819

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.