Evidence map›Paper›PMID 34914036›Full record

ReviewInfection2022

Waves and variants of SARS-CoV-2: understanding the causes and effect of the COVID-19 catastrophe.

Vikram Thakur, Shivam Bhola, Pryanka Thakur, Sanjay Kumar Singh Patel, Saurabh Kulshrestha, Radha Kanta Ratho, Pradeep Kumar

Erratum issuedAbstract readReview
In one paragraph

Review in Infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 95 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Endotheliopathy in Acute COVID-19 and Long COVID.International journal of molecular sciences · 2023
    Pooled it
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Vikram Thakur *Department of Virology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Shivam Bhola *Faculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, India.
Pryanka Thakur *Department of Virology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Sanjay Kumar Singh PatelDepartment of Chemical Engineering, Konkuk University, Seoul, 05029, South Korea.
Saurabh KulshresthaFaculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, India.
Radha Kanta RathoDepartment of Virology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India. rathopgi@yahoo.com.
Pradeep KumarFaculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, India. pradeep.kumar@shooliniuniversity.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease-19 has left a permanent mark on the history of the human race. Severe acute respiratory syndrome coronavirus-2 is a positive-sense single-stranded RNA virus, first reported in Wuhan, China, in December 2019 and from there took over the world. Being highly susceptible to mutations, the virus's numerous variants started to appear, and some were more lethal and infectious than the parent. The effectiveness of the vaccine is also affected severely against the new variant. In this study, the infectious mechanism of the coronavirus is explained with a focus on different variants and their respective mutations, which play a critical role in the increased transmissibility, infectivity, and immune escape of the virus. As India has already faced the second wave of the pandemic, the future outlook on the likeliness of a third wave with respect to the Indian variants such as kappa, delta, and Delta Plus is also discussed. This review article aims to reflect the catastrophe of the variants of SARS-CoV-2 and the possibility of developing even more severe variants in the near future.

Indexed as

COVID-19COVID-19 VaccinesHumansMutationPandemicsSARS-CoV-2COVID-19 VaccinesImmune evasionMutationsSARS-CoV-2VaccinesVariantsWaves

Identifiers

PMID34914036
PMCPMC8675301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.