Evidence map›Paper›PMID 34914026›Full record

ArticleJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2021

Increase in cartilage degeneration in all knee compartments after failed ACL reconstruction at 4 years of follow-up.

Kathleen Andrä, Robert Prill, Enes Kayaalp, Lars Irlenbusch, Eckehard Liesaus, Tilo Trommer, Peter Ullmann, Roland Becker

Abstract read
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In one paragraph

Article in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. TJournal of magnetic resonance imaging : JMRI · 2025
    Article
  4. [Revision of anterior cruciate ligament reconstruction: Interpretation of the consensus by the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA)].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
  5. Article
  6. Time to focus on ACL revision: ESSKA 2022 consensus.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Article
  7. Article
  8. Article
  9. Management of anterior cruciate ligament revision in adults: the 2022 ESSKA consensus: part II-surgical strategy.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathleen AndräCenter of Orthopaedics and Traumatology, University of Brandenburg, Medical School "Theodor Fontane", Hochstrasse 29, 14770, Brandenburg an der Havel, Germany.
Robert PrillCenter of Orthopaedics and Traumatology, University of Brandenburg, Medical School "Theodor Fontane", Hochstrasse 29, 14770, Brandenburg an der Havel, Germany.
Enes KayaalpDepartment of Orthopedics and Traumatology, Istanbul Taksim Training and Research Hospital, Siraselviler Cad, Beyoglu, Istanbul, 34433, Turkey.
Lars IrlenbuschSportsClinic Erfurt, Erfurt, Germany.
Eckehard LiesausSportsClinic Erfurt, Erfurt, Germany.
Tilo TrommerSportsClinic Erfurt, Erfurt, Germany.
Peter UllmannSportsClinic Erfurt, Erfurt, Germany.
Roland BeckerCenter of Orthopaedics and Traumatology, University of Brandenburg, Medical School "Theodor Fontane", Hochstrasse 29, 14770, Brandenburg an der Havel, Germany. Roland.Becker@mhb-fontane.de.ORCID http://orcid.org/0000-0003-1833-7608

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDegeneration of the cartilage after anterior cruciate ligament reconstruction (ACL-R) is known, and further deterioration can be expected in patients with tunnel malplacement or partial meniscal resection. It was hypothesized that there is a significant increase in cartilage degeneration after failed ACL-R. MATERIAL AND

methodsIsolated ACL revision surgery was performed in 154 patients at an interval of 46 ± 33 months (5-175 months) between primary and revision surgery. Cartilage status at the medial, lateral femorotibial, and patellofemoral compartments were assessed arthroscopically during primary and revision ACL-R in accordance with the Outerbridge classification. Tunnel placement, roof angle, and tibial slope was measured using anteroposterior and lateral radiographic views.

resultsCartilage degeneration increased significantly in the medial femorotibial compartment, followed by the lateral and patellofemoral compartments. There was a correlation between both cartilage degeneration in the patellofemoral compartment (PFC) (r DISCUSSION: Accelerated cartilage degeneration and high prevalence of meniscal lesions are seen in failed ACL-R. Tunnel placement showed significant impact on cartilage degeneration and may partially explain the increased risk of an inferior outcome when revision surgery is required after failed primary ACL-R. LEVEL OF EVIDENCE: Level IV-retrospective cohort study.

Indexed as

CartilageFollow-Up StudiesHumansRetrospective StudiesACLAnterior cruciate ligament reconstructionCartilage degenerationFailureMeniscal lesionRevisionTunnel placement

Identifiers

PMID34914026
PMCPMC8677851

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.