Evidence map›Paper›PMID 34913738›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2022

Evaluating the 35°C wet-bulb temperature adaptability threshold for young, healthy subjects (PSU HEAT Project).

Daniel J Vecellio, S Tony Wolf, Rachel M Cottle, W Larry Kenney

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 201 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Increased Vulnerability to Dehydration Due to Heat Stress and Drought Across Reproductive States for Pastoralist Women in Northern Kenya.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
  5. Article
  6. Article
  7. Reclassifying lethal heat.Nature communications · 2026
    Article
  8. Can We Protect Our Hearts by Sweating Out Excess Sodium?Exercise and sport sciences reviews · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Spatiotemporal patterns of urban heat in indoor and outdoor microclimates.Environmental research letters : ERL [Web site] · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniel J VecellioCenter for Healthy Aging, Pennsylvania State University, University Park, Pennsylvania.ORCID 0000-0001-9431-0744
S Tony WolfDepartment of Kinesiology, Pennsylvania State University, University Park, Pennsylvania.ORCID 0000-0002-6336-2143
Rachel M CottleDepartment of Kinesiology, Pennsylvania State University, University Park, Pennsylvania.ORCID 0000-0002-6567-9785
W Larry KenneyCenter for Healthy Aging, Pennsylvania State University, University Park, Pennsylvania.
Pennsylvania State University · US

Funding

Psychosocial Determinants and Biological Pathway to Healthy Aging (Pathways)T32AG049676 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI LYNN M. MARTIRE · 2016 to 2026
$3.9M
Identification of Critical Thermal Environments for Aged AdultsR01AG067471 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI KENNEY, W. LARRY · 2020 to 2024
$3.7M
NIA NIH HHS R01 AG067471NIA NIH HHS T32 AG049676NIH HHS R01AG067471NIH HHS T32AG049676
6 · The paper itself

Abstract

A wet-bulb temperature of 35°C has been theorized to be the limit to human adaptability to extreme heat, a growing concern in the face of continued and predicted accelerated climate change. Although this theorized threshold is based in physiological principles, it has not been tested using empirical data. This study examined the critical wet-bulb temperature (T

Indexed as

Heat Stress DisordersHot TemperatureAdultBody Temperature RegulationHealthy VolunteersHumansHumidityTemperatureclimate changeenvironmental limitsglobal warminghuman heat stressthermoregulation

Identifiers

PMID34913738
PMCPMC8799385
OpenAlexW4200248661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.