Observational studyClinical cardiology2022
Symptoms and health-related quality of life 5 years after catheter ablation of atrial fibrillation.
Observational study in Clinical cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Predictors of quality of life after cardiac procedures: a mixed-methods study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- A Comparative Analysis of the Effects of Cardioversion and Ablation on Anxiety, Sleep, and Quality of Life in Patients Diagnosed With Atrial Fibrillation.Clinical cardiology · 2026Article
- Determinants of symptom relief and quality of life improvement after atrial fibrillation ablation.European heart journal. Quality of care & clinical outcomes · 2026Article
- Cardiac rehabilitation in atrial fibrillation: a protocol for a Danish survey and registry-based study (PRIME-AF).BMJ open · 2025Article
- Predicting patient-related outcomes after atrial fibrillation ablation: insights from explainable artificial intelligence and digital health.European heart journal. Digital health · 2025Article
- Patient-Reported Outcomes After First Pulmonary Vein Isolation for ParoxYsmal Atrial Fibrillation: Cryoballoon vs. Radiofrequency (SPY-AF).Journal of clinical medicine · 2025Article
- Core and bridging symptoms in patients with atrial fibrillation: a network analysis.Frontiers in cardiovascular medicine · 2025Article
- Identification and Functional Investigation ofDiagnostics (Basel, Switzerland) · 2024Article
- Patient report outcomes in cryoballoon ablation of atrial fibrillation during the COVID Era: Insights from the 1STOP project.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Article
- Haemodynamic changes after atrial fibrillation initiation in patients eligible for catheter ablation: a randomized controlled study.European heart journal open · 2023Article
- Symptoms and health-related quality of life 5 years after catheter ablation of atrial fibrillation.Clinical cardiology · 2022Observational
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the effect of catheter ablation (CA) on symptoms and health-related quality of life (HRQoL) after 5 years, and analyze predictors of recurrence of symptoms.
backgroundThe primary indication for CA of atrial fibrillation (AF) is to reduce symptoms and improve HRQoL where long-term follow-up are sparse.
methodsIn this observational, long-term, single-center study, patients were recruited from Linköping University Hospital, Sweden. They were aged ≥18 years and had been referred for CA from November 2011 until June 2019. Arrhythmia-specific symptoms and HRQoL were assessed by patient-reported outcome measures (PROMs) with the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia (ASTA).
resultsIn the study were 1521 patients, 69% men, mean age 62 years. At baseline, 87% of the patients and at the 5-year follow-up 80% of those eligible filled out the ASTA questionnaire. At follow-up, 50% reported freedom from symptoms, 18% had >50% symptom reduction, 14% had a minor reduction, while 18% reported no effect or a worsening of symptoms. Factors predicting symptoms were female gender (hazard ratio [HR]: 1.8; 1.2-2.8), body mass index ≥ 35 (HR: 3.9; 1.6-9.8), and ischemic heart disease (IHD) (HR: 2.6; 1.2-5.9). After 5 years, breathlessness during activity, weakness/fatigue, and tiredness were still the most common symptoms; regarding HRQoL they were impaired physical ability and deteriorated life situation. CONCLUSIONS AND CLINICAL IMPLICATIONS: This clinical cohort of patients with AF evaluated through PROMs showed that CA had long-lasting effects on symptoms and HRQoL and that the use of PROMs in clinical routines was feasible. Factors predicting symptoms after CA were female gender, IHD, and obesity, an important reminder to encourage lifestyle management.
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