ArticleeLife2021
Neural correlates and determinants of approach-avoidance conflict in the prelimbic prefrontal cortex.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Top-down corticostriatal control of adaptive restraint during motivational conflict.Science advances · 2026Article
- Beyond Fear Learning in Isolation: Integration of Social Dimensions into Aversive Learning.Current protocols · 2026Review
- Aberrant Medial Prefrontal Cortex Activity and Flexible Behavior in the TgF344-AD Rat Model of Alzheimer's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Prefrontal chandelier cells encode stimulus salience to influence learning in male mice.Nature communications · 2026Article
- A shared ensemble in the prelimbic cortex links impulsivity and anxiety-like behavior.bioRxiv : the preprint server for biology · 2025Article
- Divergent prefrontal cortex circuits regulate cued food seeking under distinct metabolic or emotional states.Nature communications · 2025Article
- Theta-encoded information flow from dorsal CA1 to prelimbic cortex drives memory reconsolidation.iScience · 2025Article
- Sex differences in oscillatory signaling dynamics in the prelimbic cortex and nucleus accumbens core during negative affect.Behavioural brain research · 2025Article
- Functional properties of corticothalamic circuits targeting paraventricular thalamic neurons.Neuron · 2024Article
- The Switchmaze: an open-design device for measuring motivation and drive switching in mice.Peer community journal · 2024Article
- Article
- Estimating foraging behavior in rodents using a modified paradigm measuring threat imminence dynamics.Neurobiology of stress · 2024Article
- Medial prefrontal cortex suppresses reward-seeking behavior with risk of punishment by reducing sensitivity to reward.Frontiers in neuroscience · 2024Article
- Article
- Stress, associative learning, and decision-making.Neurobiology of learning and memory · 2023Review
- Validation of the neuroconnective endophenotype questionnaire (NEQ): a new clinical tool for medicine and psychiatry resulting from the contribution of Ehlers-Danlos syndrome.Frontiers in medicine · 2023Article
- Prelimbic cortex neural encoding dynamically tracks expected outcome value.Physiology & behavior · 2022Article
- A Corticothalamic Circuit Trades off Speed for Safety during Decision-Making under Motivational Conflict.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The recollection of environmental cues associated with threat or reward allows animals to select the most appropriate behavioral responses. Neurons in the prelimbic (PL) cortex respond to both threat- and reward-associated cues. However, it remains unknown whether PL regulates threat-avoidance vs. reward-approaching responses when an animals' decision depends on previously associated memories. Using a conflict model in which male Long-Evans rats retrieve memories of shock- and food-paired cues, we observed two distinct phenotypes during conflict: (1) rats that continued to press a lever for food (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.