SynthesisEuropean psychiatry : the journal of the Association of European Psychiatrists2021
Early Intervention in Psychosis services: A systematic review and narrative synthesis of the barriers and facilitators to implementation.
Synthesis in European psychiatry : the journal of the Association of European Psychiatrists, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Early interventions for first onset of symptoms of mental health conditions: an umbrella review of systematic reviews.BMC medicine · 2026Pooled it
- Clinical practice guidelines and quality standards for early intervention in psychosis: an AGREE II appraisal and systematic review of service components.Frontiers in psychiatry · 2026Pooled it
- Effectiveness of antipsychotic drug therapy for treating psychosis in people with epilepsy: A systematic review.Epilepsia · 2024Pooled it
- Digital Health Interventions for Informal Family Caregivers of People With First-Episode Psychosis: Systematic Review on User Experience and Effectiveness.JMIR mental health · 2024Pooled it
- Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review.Schizophrenia bulletin · 2024Pooled it
- Early intervention in psychosis services: A systematic review and narrative synthesis of barriers and facilitators to seeking access.European psychiatry : the journal of the Association of European Psychiatrists · 2023Pooled it
- The influence of clinical and sociodemographic variables on employment and education for Danish youth with a psychotic disorder: a population-based national registry study.Social psychiatry and psychiatric epidemiology · 2026Article
- Using smartphone-based assessment of social experience to predict relapse in first-episode psychosis.Schizophrenia (Heidelberg, Germany) · 2026Article
- A Fidelity Assessment of Early Psychosis Intervention Services in British Columbia, Canada.Early intervention in psychiatry · 2026Article
- Care Pathway for Early Intervention in Psychiatry: A Community Mental Healthcare Initiative to Overcome the Treatment Gap in Hauts-de-Seine, France.Early intervention in psychiatry · 2026Article
- Real-world comprehensive care of people living with schizophrenia: recommendations across different settings and clinical stages.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- PATIENT PATHWAYS TO UGANDA'S FIRST SPECIALISED EARLY INTERVENTION IN PSYCHOSIS SERVICE AND RELATION TO THEIR CLINICAL OUTCOMES.medRxiv : the preprint server for health sciences · 2026Article
- Identifying Research Priorities in Early Psychosis: A Collaborative Approach to Shaping the Future of Early Psychosis Clinical Trials in Australia.Early intervention in psychiatry · 2026Article
- Overcoming Patient Access Barriers in Complex Conditions: Lessons from Schizophrenia for Broader Healthcare Applications.Journal of market access & health policy · 2026Article
- Availability and effectiveness of multicomponent interventions for early psychosis in 20 low-income and middle-income countries: a systematic review.EClinicalMedicine · 2026Article
- Virtual Delivery of Early Psychosis Care: Retrospective Cohort Study of Factors Associated With Initial Engagement.Journal of medical Internet research · 2026Article
- Lurasidone continuation in real-world clinical cases in Japan: retrospective study of factors associated with six-month persistence.Annals of general psychiatry · 2026Article
- The Vital Role of Research in Transforming Mental Health in Aotearoa New Zealand.Journal of the Royal Society of New Zealand · 2026Article
- Factors that affect pathways to care for youth with psychotic disorders in Newfoundland and Labrador, Canada: A qualitative study.PLOS mental health · 2026Article
- Stepped care involving cognitive behavioral therapy for young people at clinical high-risk for psychosis in community settings: longitudinal intervention study protocol.BMC psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly intervention in psychosis (EIP) services target the early manifestation of psychosis and provide multidisciplinary care. They demonstrate effectiveness and cost-effectiveness. Implementation of EIP services is inconsistent and piecemeal. This systematic review and narrative synthesis aims to identify barriers and facilitators to EIP service implementation.
methodsWe conducted an electronic search of databases (EMBASE, Medline, Web of Science, and PsychINFO) to detect papers reporting EIP service implementation findings and associated barriers and facilitators. The search occurred between June to August 2020, and again in January 2021. Articles meeting inclusion criteria were extracted and narratively synthesized. A quality assessment was conducted using the Mixed Methods Appraisal Tool.
resultsTwenty-three studies were selected. The most common study design was descriptive accounts of implementation. Patient age ranged varied from 14 to 35 years. We identified three barrier and facilitator domains: (a) system; (b) services; and (c) staff, and a range of subdomains. The most frequent subdomains were "funding" and "strength of collaboration and communication between EIP and outside groups and services". Associations between domains and subdomains were evident, particularly between systems and services.
conclusionsA range of barriers and facilitators to EIP implementation exist. Some of these are generic factors germane across health systems and services, while others are specific to EIP services. A thorough prior understanding of these challenges and enablers are necessary before implementation is attempted. Accounting for these issues within local and national contexts may help predict and increase the likelihood of services' success, stability, and longevity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.