Evidence map›Paper›PMID 34913282›Full record

ArticleYonsei medical journal2022

Gut Microbiome in Probable Intestinal Tuberculosis and Changes following Anti-Tuberculosis Treatment.

Hyuk Yoon, Young Soo Park, Cheol Min Shin, Nayoung Kim, Dong Ho Lee

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Observational
  3. Microbiome of lovebug (Microbiology spectrum · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. The gut microbiome: A line of defense against tuberculosis development.Frontiers in cellular and infection microbiology · 2023
    Review
  9. TheAccess microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hyuk YoonDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0002-2657-0349
Young Soo ParkDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. dkree@snubh.org.ORCID https://orcid.org/0000-0003-1893-7726
Cheol Min ShinDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0003-2265-9845
Nayoung KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0002-9397-0406
Dong Ho LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0002-6376-410X
Seoul National University · KRSeoul National University Bundang Hospital · KR

Funding

National Research Foundation of Korea 2016M3A9F3947027Seoul National University Bundang Hospital 02-2016-043
6 · The paper itself

Abstract

purposeInformation on the gut microbiome in patients with intestinal tuberculosis (ITB) and changes therein following anti-tuberculosis treatment (ATT) is lacking. We aimed to elucidate differences in stool microbiome between ITB patients and controls and to evaluate stool microbiome changes after ATT. MATERIALS AND

methodsEleven patients with probable ITB underwent ATT for 6 months, with stool samples collected at 0, 2, and 6 months. We performed next-generation sequencing of 16S rRNA genes in stool bacteria and compared the gut microbiome.

resultsInitially, the relative abundance of

conclusionThere were no significant differences in alpha- and beta-diversity in the stool microbiome at 0, 2, and 6 months after ATT. The stool microbiome composition of probable ITB patients was different from that of controls, and 6 months of ATT did not significantly affect it.

Indexed as

Gastrointestinal MicrobiomeTuberculosisAntitubercular AgentsFecesHumansRNA, Ribosomal, 16SAntitubercular AgentsRNA, Ribosomal, 16SDrug therapygastrointestinal tuberculosismicrobiota

Identifiers

PMID34913282
PMCPMC8688367
OpenAlexW4200513176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.