ArticleMethods in molecular biology (Clifton, N.J.)2022
Live Imaging of the Dynamics of Mammalian Neural Crest Cell Migration.
Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- The Sh3Pxd2bnee-/- mouse reveals developmental features of Frank-ter Haar syndrome.Development (Cambridge, England) · 2026Article
- Cell extrusion drives neural crest cell delamination.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Cell extrusion - a novel mechanism driving neural crest cell delamination.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neural crest cells (NCC) are a multipotent cell population that play an important role in vertebrate development. Often touted as the fourth-germ layer, NCC are induced at the border of the neural and non-neural ectoderm during the neurulation phase of embryogenesis. NCC undergo an epithelial to mesenchymal transition (EMT) that facilitates their delamination and migration throughout the embryo. After reaching their final destination, NCC then differentiate into numerous distinct cell types including neurons and glia, melanocytes, and craniofacial chondrocytes and osteoblasts. Research into the signals and mechanisms regulating each step of NCC development has been instrumental to our understanding of vertebrate development, evolution, and disease. However, studying the single and collective cellular dynamics of mammalian NCC migration has proven difficult due to the challenges accessing, and limitations visualizing, NCC within an embryo that develops in utero. The following chapter describes methods for studying the dynamics of cranial NCC migration in whole mouse embryos and in two-dimensional (2D) and 3D explant cultures of the neural plate, but these methods can be adapted for NCC at any axial level of the embryo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.