Evidence map›Paper›PMID 34913064›Full record

ArticleMolecular medicine reports2022

Substance P prevents doxorubicin‑induced cardiomyocyte injury by regulating apoptosis and autophagy:

Fa-Xiu Chen, Qin Wan, Qing-Ling Li, Jing Fang, Le Peng, Jian Hu

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Doxorubicin-Induced Cardiotoxicity: A Comprehensive Update.Journal of cardiovascular development and disease · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fa-Xiu ChenDepartment of Geriatrics and Gerontology, People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Qin WanDepartment of Geriatrics and Gerontology, People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Qing-Ling LiDepartment of Geriatrics and Gerontology, People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Jing FangDepartment of Geriatrics and Gerontology, People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Le PengDepartment of Geriatrics and Gerontology, People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Jian HuDepartment of Geriatrics and Gerontology, People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The function of substance P (SP) in myocardial ischemia is well understood, but its effects on congestive heart failure are unclear. The present study aimed to use

Indexed as

AnimalsApoptosisAutophagyCardiotoxicityCell LineDisease Models, AnimalDoxorubicinHeart FailureHumansMaleMyocytes, CardiacRatsSubstance PDoxorubicinSubstance Papoptosisautophagyheart failuresubstance P

Identifiers

PMID34913064
PMCPMC8711026
OpenAlexW4200120640

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.