Evidence map›Paper›PMID 34913048›Full record

ArticleFrontiers in genome editing2021

Targeted Knockout of Eukaryotic Translation Initiation Factor 4E Confers Bymovirus Resistance in Winter Barley.

Robert Eric Hoffie, Ingrid Otto, Dragan Perovic, Nagaveni Budhagatapalli, Antje Habekuß, Frank Ordon, Jochen Kumlehn

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genome editing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

  1. Candidate genes for stem rust resistance in Italian ryegrass revealed by nested association mapping.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  2. Review
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  4. Targeted mutagenesis ofaBIOTECH · 2025
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  5. Article
  6. Strategies for plant-virus disease management from gene editing to nanotechnology.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  7. Genetic and physical localization of a leaf rust susceptibility gene in barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Robert Eric HoffiePlant Reproductive Biology, Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany.
Ingrid OttoPlant Reproductive Biology, Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany.
Dragan PerovicInstitute for Resistance Research and Stress Tolerance, Julius Kuehn Institute (JKI), Federal Research Centre for Cultivated Plants, Quedlinburg, Germany.
Nagaveni BudhagatapalliPlant Reproductive Biology, Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany.
Antje HabekußInstitute for Resistance Research and Stress Tolerance, Julius Kuehn Institute (JKI), Federal Research Centre for Cultivated Plants, Quedlinburg, Germany.
Frank OrdonInstitute for Resistance Research and Stress Tolerance, Julius Kuehn Institute (JKI), Federal Research Centre for Cultivated Plants, Quedlinburg, Germany.
Jochen KumlehnPlant Reproductive Biology, Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany.
Leibniz Institute of Plant Genetics and Crop Plant Research · DEJulius Kühn-Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Eukaryotic Translation Initiation Factor 4E (EIF4E) is a well-known susceptibility factor for potyvirus infections in many plant species. The barley yellow mosaic virus disease, caused by the bymoviruses

Indexed as

Cas9CRISPRdoubled haploidgenome editingprotoplastsRNA-guided endonucleasestargeted mutagenesis

Identifiers

PMID34913048
PMCPMC8667817
OpenAlexW3216564832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.