Evidence map›Paper›PMID 34913021›Full record

ArticleJournal of the Endocrine Society2022

Insulin Receptor Autoantibody-mediated Hypoglycemia in a Woman With Mixed Connective Tissue Disease.

Max C Petersen, Jonah M Graves, Tony Yao, Lutz Schomburg, Waldemar B Minich, Deborah L Parks, Janet B McGill, Maamoun Salam

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of the Endocrine Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Aptamers in Drug Delivery Development.Materials today (Kidlington, England) · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Max C PetersenDivision of Endocrinology, Metabolism, & Lipid Research, Washington University School of Medicine, St Louis, Missouri 63110, USA.ORCID https://orcid.org/0000-0001-8646-2377
Jonah M GravesDepartment of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Tony YaoDepartment of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA.ORCID https://orcid.org/0000-0002-8744-3597
Lutz SchomburgInstitute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany.ORCID https://orcid.org/0000-0001-9445-1555
Waldemar B MinichInstitute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany.
Deborah L ParksDivision of Rheumatology, Washington University School of Medicine, St Louis, MO 63110, USA.ORCID https://orcid.org/0000-0003-3276-6855
Janet B McGillDivision of Endocrinology, Metabolism, & Lipid Research, Washington University School of Medicine, St Louis, Missouri 63110, USA.ORCID https://orcid.org/0000-0002-6228-6521
Maamoun SalamDivision of Endocrinology, Metabolism, & Lipid Research, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Washington University in St. Louis · USCharité - Universitätsmedizin Berlin · DE

Funding

WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
DIABETES &RELATED METABOLIC DISEASEST32DK007120 · NIDDK · WASHINGTON UNIVERSITY · PI MARCO COLONNA, Maria Sara Remedi · 1986 to 2026
$15.7M
NIDDK NIH HHS P30 DK020579NIDDK NIH HHS T32 DK007120
6 · The paper itself

Abstract

Autoantibodies to the insulin receptor are rare and typically cause severe insulin resistance and hyperglycemia, a condition termed

Indexed as

anti-insulin receptor antibodyautoimmune hypoglycemiamixed connective tissue diseasetype B insulin resistance

Identifiers

PMID34913021
PMCPMC8668203
OpenAlexW3217071499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.