Evidence map›Paper›PMID 34913014›Full record

ArticleAsiaIntervention2021

Transcatheter aortic valve replacement for aortic regurgitation in Asians: TAVR for aortic regurgitation in Asians.

Erica L Soong, Yi Jing Ong, Jamie S Y Ho, Nichola W S Chew, William K F Kong, Tiong-Cheng Yeo, Ping Chai, Edgar L W Tay, Kent Tan, Yinghao Lim and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in AsiaIntervention, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Erica L SoongYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Yi Jing OngYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Jamie S Y HoAcademic Foundation Programme, North Middlesex University Hospital NHS Trust, London, United Kingdom.
Nichola W S ChewDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
William K F KongDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Tiong-Cheng YeoDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Ping ChaiDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Edgar L W TayDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Kent TanDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Yinghao LimDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Ivandito KuntjoroDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Ching-Hui SiaDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
National University Heart Centre Singapore · SGNational University of Singapore · SGNorth Middlesex University Hospital NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsAlthough surgical aortic valve replacement (SAVR) is currently the recommended intervention for patients with native AR without aortic stenosis, a significant proportion of Asian patients undergo transcatheter aortic valve replacement (TAVR), which has not been studied fully for safety and outcomes. This systematic review aims to examine the characteristics and outcomes of Asian patients with pure native aortic regurgitation (AR) undergoing TAVR. METHODS AND

resultsPubMed, Embase, Scopus, Web of Science and Cochrane CENTRAL were systematically searched for randomised controlled trials, observational studies and case reports published  from inception to 2 April 2020, involving patients of Asian ethnicity with pure native aortic regurgitation who had undergone TAVR. Our primary outcome was all-cause mortality, with secondary outcomes including all major complications. Five studies (n=274 patients) and eight case reports were included. Device success was reported in 94.9% of the patients, the all-cause mortality rate was 4.4%, 2.5% were converted to SAVR, 1.7% had post-operative paravalvular leak and 6.7% required permanent pacemaker implantation.

conclusionsTAVR has demonstrated acceptable safety and efficacy in Asian patients with pure AR displaying low mortality rates and few adverse outcomes.

Identifiers

PMID34913014
PMCPMC8670568
OpenAlexW3217299548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.