Evidence map›Paper›PMID 34912880›Full record

ArticleERJ open research2021

Clinical value of bronchodilator response for diagnosing asthma in steroid-naïve adults.

Leena E Tuomisto, Pinja Ilmarinen, Lauri Lehtimäki, Onni Niemelä, Minna Tommola, Hannu Kankaanranta

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. From FEVJournal of asthma and allergy · 2026
    Review
  3. Article
  4. Article
  5. Prevalence, Diagnostic Utility and Associated Characteristics of Bronchodilator Responsiveness.American journal of respiratory and critical care medicine · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Leena E TuomistoDept of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland.ORCID https://orcid.org/0000-0001-6990-4508
Pinja IlmarinenDept of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland.ORCID https://orcid.org/0000-0002-8758-2431
Lauri LehtimäkiFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Onni NiemeläFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Minna TommolaDept of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland.ORCID https://orcid.org/0000-0003-4201-389X
Hannu KankaanrantaDept of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland.
Tampere University · FISeinäjoki University of Applied Sciences · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spirometry and testing for bronchodilator response have been recommended to detect asthma, and a bronchodilator response (BDR) of ≥12% and ≥200 mL has been suggested to confirm asthma. However, the clinical value of bronchodilation tests in newly diagnosed steroid-naïve adult patients with asthma remains unknown. We evaluated the sensitivity of BDR in forced expiratory volume in 1 s (FEV

Identifiers

PMID34912880
PMCPMC8666574
OpenAlexW3206636101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.