Evidence map›Paper›PMID 34912870›Full record

ArticleFrontiers in cardiovascular medicine2021

Uncovering the Role of Gut Microbiota in Amino Acid Metabolic Disturbances in Heart Failure Through Metagenomic Analysis.

Tomohiro Hayashi, Tomoya Yamashita, Tomoya Takahashi, Tokiko Tabata, Hikaru Watanabe, Yasuhiro Gotoh, Masakazu Shinohara, Kenjiro Kami, Hidekazu Tanaka, Kensuke Matsumoto and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
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  5. Preparation and Properties ofInternational journal of food science · 2026
    Article
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  7. Aspartate Is A Determinant of TNF-α Biogenesis in Sub-Saharan Africa: Insight Into the Pathogenesis of Noncommunicable Diseases.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  8. Review
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  14. Article
  15. Bioscience of microbiota, food and health · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Tomohiro HayashiDivision of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Tomoya YamashitaDivision of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Tomoya TakahashiSchool of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
Tokiko TabataDivision of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Hikaru WatanabeSchool of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
Yasuhiro GotohDepartment of Bacteriology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.
Masakazu ShinoharaDivision of Epidemiology, Kobe University Graduate School of Medicine, Kobe, Japan.
Kenjiro KamiHuman Metabolome Technologies, Tsuruoka, Japan.
Hidekazu TanakaDivision of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Kensuke MatsumotoDivision of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Tetsuya HayashiDepartment of Bacteriology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.
Takuji YamadaSchool of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
Ken-Ichi HirataDivision of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Kobe University · JPKyushu University · JPTokyo Institute of Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

amino acid (AA)gut microbiotaheart failuremetabolismmetagenomic analysis

Identifiers

PMID34912870
PMCPMC8667331
OpenAlexW3217129551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.