Evidence map›Paper›PMID 34912808›Full record

ReviewFrontiers in cell and developmental biology2021

It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom.

Veronica G Martinez Acosta, Fausto Arellano-Carbajal, Kathy Gillen, Kay A Tweeten, Eduardo E Zattara

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. DHEA inhibits regeneration inmicroPublication biology · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Veronica G Martinez AcostaDepartment Biology, University of the Incarnate Word, San Antonio, TX, United States.
Fausto Arellano-CarbajalFacultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro, Mexico.
Kathy GillenDepartment of Biology, Kenyon College, Gambier, OH, United States.
Kay A TweetenDepartment of Biology, St. Catherine University, St. Paul, MN, United States.
Eduardo E ZattaraInstituto de Investigaciones en Biodiversidad y Medio Ambiente, CONICET-Universidad Nacional del Comahue, Buenos Aires, Argentina.
Autonomous University of Queretaro · MXConsejo Nacional de Investigaciones Científicas y Técnicas · ARKenyon College · USSt. Catherine University · USUniversity of the Incarnate Word · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms supporting regeneration and successful recovery of function have fascinated scientists and the general public for quite some time, with the earliest description of regeneration occurring in the 8th century BC through the Greek mythological story of Prometheus. While most animals demonstrate the capacity for wound-healing, the ability to initiate a developmental process that leads to a partial or complete replacement of a lost structure varies widely among animal taxa. Variation also occurs within single species based on the nature and location of the wound and the developmental stage or age of the individual. Comparative studies of cellular and molecular changes that occur both during, and following, wound healing may point to conserved genomic pathways among animals of different regenerative capacity. Such insights could revolutionize studies within the field of regenerative medicine. In this review, we focus on several closely related species of

Indexed as

clitellateinvertebrate biologymolecular resourcesneurophysiologystem cellsSTEM education

Identifiers

PMID34912808
PMCPMC8667080
OpenAlexW3216917859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.