Evidence map›Paper›PMID 34912736›Full record

ArticleEuropean journal of case reports in internal medicine2021

Autoimmune Thrombocytopenia in SLE and COVID-19.

Yeremia Suryo Pratama, Riska Pradiptakirana, Azkia Rachmah, Nurhasan Agung Prabowo

4 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05766176 completednot on this mapstarted 2022, after this paper: background citation

Study of the Effectiveness of The COVID-19 Vaccine

TypeobservationalSponsorUniversitas Sebelas MaretRan2022 to 2022Enrolled100ConditionsCOVID-19ArmsCOVID-19 Antibody
NCT05921058 phase1 / phase2completednot on this mapstarted 2022, after this paper: background citation

The Effects of Mesenchymal Stem Cell Secretome in Lupus Patients

TypeinterventionalSponsorUniversitas Sebelas MaretRan2022 to 2023Enrolled15ConditionsLupus ErythematosusArmsSecretome, Placebo
NCT05925647 phase1 / phase2completednot on this mapstarted 2022, after this paper: background citation

The Effects of Mesenchymal Stem Cell Secretome in Rheumatoid Arthritis Patients

TypeinterventionalSponsorUniversitas Sebelas MaretRan2022 to 2023Enrolled15ConditionsRheumatoid ArthritisArmsMessenchymal stem cell secretome, Placebo
NCT05943405 completednot on this mapstarted 2022, after this paper: background citation

The Disease Severity In Patients With Psoriasis

TypeobservationalSponsorUniversitas Sebelas MaretRan2022 to 2022Enrolled33ConditionsPsoriasis
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yeremia Suryo PratamaFaculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Riska PradiptakiranaFaculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Azkia RachmahFaculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Nurhasan Agung PrabowoInternal Medicine Department, Faculty of Medicine, Sebelas Maret University Hospital, Surakarta, Indonesia.
Sebelas Maret University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombocytopenia and hypercoagulopathy are haematological abnormalities commonly seen in individuals with coronavirus disease 2019 (COVID-19) and systemic lupus erythematosus (SLE). The difficulty arises when the patient has both diseases concurrently. The clinician should be able to comprehend the pathophysiology of these patient abnormalities in order to provide the best treatment possible. We present a case of a 20-year-old female COVID-19 patient with a history of SLE who had thrombocytopenia but normal D-dimer results. Our analysis revealed that the thrombocytopenia may have been caused by a relapse of lupus, not by COVID-19 infection. In this case, glucocorticoids were the primary therapy and produced excellent results. LEARNING POINTS: The pathophysiology of thrombocytopenia in a patient with concurrent COVID-19 and SLE should not always be associated with platelet consumption.Low-dose glucocorticoids should be administered, with infection risk and comorbidities taken into consideration.Glucocorticoid therapy may result in a delay in viral clearance.

Indexed as

COVID-19hypercoagulopathySLEthrombocytopenia

Identifiers

PMID34912736
PMCPMC8668010
OpenAlexW3209252481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.