ArticleFrontiers in plant science2021
Integrated Transcriptome Analysis and Single-Base Resolution Methylomes of Watermelon (
Article in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Genome-wide identification of the GATA transcription factor family in ten Cucurbitaceae species and expression analysis of ClGATA genes in watermelon stress responses.BMC genomics · 2026Article
- Genome-wide identification of HXK gene families in cucumber and watermelon: CsHXK1 and ClHXK6 play key roles in responding to multiple stresses.BMC plant biology · 2026Article
- The DIR Gene Family in Watermelon: Evolution, Stress Expression Profiles, and Functional Exploration ofInternational journal of molecular sciences · 2025Article
- Transcription factor ClTCP4 maintains watermelon resilience to drought by stabilizing antioxidant and photosynthetic systems.Plant cell reports · 2025Article
- Watermelon fruit metabolome gene discovery and its application in breeding: a review.Frontiers in plant science · 2025Review
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
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Abstract
DNA methylation plays an important role against adverse environment by reshaping transcriptional profile in plants. To better understand the molecular mechanisms of watermelon response to osmotic stress, the suspension cultured watermelon cells were treated with 100mM mannitol, and then a methylated cytosines map was generated by whole genome bisulfite sequencing (WGBS). Combined with transcriptome sequencing, the effects of osmotic stress on differentially methylated expressed genes (DMEGs) were assessed. It was found that genes related to plant hormone synthesis, signal transduction, osmoregulatory substance-related and reactive oxygen species scavenging-related enzyme could rapidly respond to osmotic stress. The overall methylation level of watermelon decreased after osmotic stress treatment, and demethylation occurred in CG, CHG, and CHH contexts. Moreover, differentially methylated expressed genes (DMEGs) were significantly enriched in RNA transport, starch and sucrose metabolism, plant hormone signal transduction and biosynthesis of secondary metabolites, especially in biosynthesis of osmolytes synthase genes. Interestingly, demethylation of a key enzyme gene
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Registered trials
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