Evidence map›Paper›PMID 34912241›Full record

ArticleFrontiers in physiology2021

Application of Metabolomics to Identify Potential Biomarkers for the Early Diagnosis of Coronary Heart Disease.

Huali Jiang, Li Li, Weijie Chen, Benfa Chen, Heng Li, Shanhua Wang, Min Wang, Yi Luo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Emerging Roles of Long Non-Coding RNAs in Cardiovascular Diseases.Journal of cellular and molecular medicine · 2025
    Review
  3. Identification of potential biomarkers for coronary slow flow using untargeted metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Huali JiangDepartment of Cardiovascularology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Li LiDepartment of Cardiovascularology, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, China.
Weijie ChenDepartment of Cardiovascularology, Dongguan Tungwah Hospital, Dongguan, China.
Benfa ChenDepartment of Cardiovascularology, Dongguan Tungwah Hospital, Dongguan, China.
Heng LiDepartment of Cardiovascularology, Dongguan Tungwah Hospital, Dongguan, China.
Shanhua WangDepartment of Cardiovascularology, Dongguan Tungwah Hospital, Dongguan, China.
Min WangDepartment of Cardiovascularology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yi LuoDepartment of Cardiovascularology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
First Affiliated Hospital of Guangzhou Medical University · CNFirst Affiliated Hospital of Jinan University · CNGuangzhou First People's Hospital · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary heart disease (CHD) is one of the leading causes of deaths globally. Identification of serum metabolic biomarkers for its early diagnosis is thus much desirable. Serum samples were collected from healthy controls (

Indexed as

biomarkerscoronary heart diseaseliquid chromatographymass spectrometrymetabolomics

Identifiers

PMID34912241
PMCPMC8667077
OpenAlexW3216129070

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.