Evidence map›Paper›PMID 34912225›Full record

ArticleFrontiers in pharmacology2021

Danzhi Xiaoyao Powder Promotes Neuronal Regeneration by Downregulating Notch Signaling Pathway in the Treatment of Generalized Anxiety Disorder.

Chao Liu, Zhenhao Ying, Zifa Li, Long Zhang, Xin Li, Wenbo Gong, Jiang Sun, Xuejing Fan, Ke Yang, Xingchen Wang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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  10. Role of astrocytes in the pathogenesis of perinatal brain injury.Molecular medicine (Cambridge, Mass.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Chao LiuThe First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Zhenhao YingSchool of Rehabilitation Science, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Zifa LiExperimental Center, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Long ZhangThe First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Xin LiCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Wenbo GongThe First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Jiang SunThe First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Xuejing FanCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Ke YangCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Xingchen WangDepartment of Neurology, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Sheng WeiExperimental Center, Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Ning DongDepartment of Neurology, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji'nan, China.
Shandong University of Traditional Chinese Medicine · CNAffiliated Hospital of Shandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DZXYSGeneralized anxiety disorderhippocampusneuron regenerationNotch

Identifiers

PMID34912225
PMCPMC8666953
OpenAlexW3217383184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.