Evidence map›Paper›PMID 34912178›Full record

ArticleDesigned monomers and polymers2021

Fabrication, Characterization and Toxicity Evaluation of Chemically Cross linked Polymeric Network for Sustained Delivery of Metoprolol Tartrate.

Sumaira, Ume Ruqia Tulain, Alia Erum, Muhammad Ajaz Hussain, Sidra, Nadia Shamshad Malik, Ayesha Rashid, Rizwana Kausar, Nitasha Gohar, Nariman Shahid and 1 more

Abstract read
In one paragraph

Article in Designed monomers and polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. pH ResponsiveInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

SumairaFaculty of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Ume Ruqia TulainFaculty of Pharmacy, University of Sargodha, Sargodha, Pakistan.ORCID https://orcid.org/0000-0003-3771-1466
Alia ErumFaculty of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Muhammad Ajaz HussainInstitute of Chemistry, University of Sargodha, Sargodha, Pakistan.ORCID https://orcid.org/0000-0003-4570-6616
SidraFaculty of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Nadia Shamshad MalikFaculty of Pharmacy, Capital University of Science and Technology, Islamabad, Pakistan.
Ayesha RashidDepartment of Pharmacy, Women University Multan, Multan, Pakistan.
Rizwana KausarIlm College of Pharmaceutical Sciences, Sargodha, Pakistan.
Nitasha GoharFaculty of Pharmacy, Capital University of Science and Technology, Islamabad, Pakistan.
Nariman ShahidFaculty of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Mahwish SiddiquiFaculty of Pharmacy, Capital University of Science and Technology, Islamabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural mucilages are auspicious biodegradable polymeric materials. The aim of the present research work was to elucidate the characteristics of quince mucilage-based polymeric network for sustained delivery of metprolol tartrate and its toxicity evaluation. Mucilage was extracted by hot water extraction, and characterization of quince mucilage was accomplished by using Fourier transform infrared (FTIR) spectroscopy. Different batches of quince mucilage polymeric network were prepared by free radical polymerization by utilizing varying ratios of quince mucilage, acrylamide and crosslinker. Degree of swelling depends on concentration of mucilage, monomer and also on crosslinking density of polymeric network. FTIR illustrates proficient grafting, and morphological (scanning electron microscopy) analysis signified porous design. Hence, quince mucilage-based design was encouraging for sustained delivery of metprolol tartrate and acute toxicity evaluation proved that mucilage-based network was safe for oral drug delivery system.

Indexed as

chemically crosslinkedNatural mucilagespolymeric networksustained deliverytoxicity evaluation

Identifiers

PMID34912178
PMCPMC8667954

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.