Evidence map›Paper›PMID 34912167›Full record

ArticleBreeding science2021

Targeted genome modifications in cereal crops.

Hiroshi Hisano, Fumitaka Abe, Robert E Hoffie, Jochen Kumlehn

Open access · diamondAbstract read
In one paragraph

Article in Breeding science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Rapid development of naked malting barley germplasm through targeted mutagenesis.Molecular breeding : new strategies in plant improvement · 2025
    Article
  3. Review
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  11. Functional Validation ofInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Hiroshi HisanoInstitute of Plant Science and Resources, Okayama University, Kurashiki, Okayama 710-0046, Japan.
Fumitaka AbeInstitute of Crop Science, National Agriculture and Food Research Organization, Tsukuba, Ibaraki 305-8518, Japan.
Robert E HoffieLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), D-06466 Stadt Seeland/OT Gatersleben, Germany.
Jochen KumlehnLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), D-06466 Stadt Seeland/OT Gatersleben, Germany.
Leibniz Institute of Plant Genetics and Crop Plant Research · DENational Agriculture and Food Research Organization · JPOkayama University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent advent of customizable endonucleases has led to remarkable advances in genetic engineering, as these molecular scissors allow for the targeted introduction of mutations or even precisely predefined genetic modifications into virtually any genomic target site of choice. Thanks to its unprecedented precision, efficiency, and functional versatility, this technology, commonly referred to as genome editing, has become an effective force not only in basic research devoted to the elucidation of gene function, but also for knowledge-based improvement of crop traits. Among the different platforms currently available for site-directed genome modifications, RNA-guided clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) endonucleases have proven to be the most powerful. This review provides an application-oriented overview of the development of customizable endonucleases, current approaches to cereal crop breeding, and future opportunities in this field.

Indexed as

barleyCRISPRmaizericeTALENwheatzinc-finger nucleases

Identifiers

PMID34912167
PMCPMC8661484
OpenAlexW3196809185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.