Evidence map›Paper›PMID 34912118›Full record

ArticleNature2022

Single-cell delineation of lineage and genetic identity in the mouse brain.

Rachel C Bandler, Ilaria Vitali, Ryan N Delgado, May C Ho, Elena Dvoretskova, Josue S Ibarra Molinas, Paul W Frazel, Maesoumeh Mohammadkhani, Robert Machold, Sophia Maedler and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 201 citations in OpenAlex.

  1. Article
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  13. Multimodal classification of neurons in the lateral septum.bioRxiv : the preprint server for biology · 2026
    Article
  14. Article
  15. Review
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  17. Article
  18. Article
  19. Disease insights from brain somatic mosaicism.Experimental & molecular medicine · 2026
    Review
  20. Article

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Rachel C Bandler *Max Planck Institute of Neurobiology, Martinsried, Germany.
Ilaria Vitali *Max Planck Institute of Neurobiology, Martinsried, Germany.ORCID http://orcid.org/0000-0001-9536-0292
Ryan N Delgado *Department of Anatomy, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-7551-0182
May C HoMax Planck Institute of Neurobiology, Martinsried, Germany.ORCID http://orcid.org/0000-0002-7373-2961
Elena DvoretskovaMax Planck Institute of Neurobiology, Martinsried, Germany.
Josue S Ibarra MolinasMax Planck Institute of Neurobiology, Martinsried, Germany.
Paul W FrazelNYU Neuroscience Institute, Langone Medical Center, New York, NY, USA.
Maesoumeh MohammadkhaniNYU Neuroscience Institute, Langone Medical Center, New York, NY, USA.
Robert MacholdNYU Neuroscience Institute, Langone Medical Center, New York, NY, USA.
Sophia MaedlerMax Planck Institute of Biochemistry, Martinsried, Germany.
Shane A LiddelowNYU Neuroscience Institute, Langone Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-0840-1437
Tomasz J NowakowskiDepartment of Anatomy, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-2345-4964
Gord FishellBroad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-9640-9278
Christian MayerMax Planck Institute of Neurobiology, Martinsried, Germany. cmayer@neuro.mpg.de.ORCID http://orcid.org/0000-0003-3152-5574
Max Planck Institute of Neurobiology · DENYU Langone Health · USBroad Institute · USUniversity of California, San Francisco · USMax Planck Institute of Biochemistry · DE

Funding

MEDICAL SCIENTIST TRAININGT32GM007308 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PHILIPS, MARK REID · 1985 to 2019
$23.2M
The role of genetic and activity dependent cues in the generation of 5HT3aR interneuron diversityP01NS074972 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RUDY, BERNARDO · 2012 to 2023
$15.5M
Regional and Genetic Diversity of Cortical InterneuronsR01MH071679 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FISHELL, GORDON J · 2005 to 2020
$8.5M
Development and validation of AAV vectors to manipulate specific neuronal subtypes and circuits involved in epilepsy and psychiatric disorders across mammalian species.UG3MH120096 · NIMH · BROAD INSTITUTE, INC. · PI DEVERMAN, BENJAMIN E, FISHELL, GORDON J · 2019 to 2021
$6.7M
The Development and Integration of Early Born SST-Expressing Interneurons in the CortexR01NS081297 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GORDON J FISHELL · 2012 to 2026
$6.6M
Mapping Developmental Lineage Relationships in the Cerebral CortexRF1MH121268 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NOWAKOWSKI, TOMASZ · 2019 to 2019
$2.1M
Investigating the biology of human neurotoxic reactive astrocytes using induced pluripotent stem cellsR21NS111186 · NINDS · NEW YORK STEM CELL FOUNDATION · PI FOSSATI, VALENTINA · 2019 to 2019
$521k
The genetic logic of interneuron differentiationF30MH114462 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BANDLER, RACHEL · 2017 to 2018
$84k
NIGMS NIH HHS T32 GM007308NIMH NIH HHS F30 MH114462NIMH NIH HHS R01 MH071679NIMH NIH HHS RF1 MH121268NIMH NIH HHS UG3 MH120096NINDS NIH HHS P01 NS074972NINDS NIH HHS R01 NS081297NINDS NIH HHS R21 NS111186
6 · The paper itself

Abstract

During neurogenesis, mitotic progenitor cells lining the ventricles of the embryonic mouse brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic neurons and glia

Indexed as

BrainCell LineageGABAergic NeuronsNeural Stem CellsNeurogenesisAnimalsCell DifferentiationEmbryonic DevelopmentMiceMitosisTranscriptome

Identifiers

PMID34912118
PMCPMC8770128
OpenAlexW4200449643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.