ArticleNature2022
Towards the biogeography of prokaryotic genes.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 1 pooled it
16.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
133 citing papers in PubMed, 1 synthesis or guideline pooled it, 232 citations in OpenAlex.
- Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson's disease.Nature communications · 2025Pooled it
- The postbiotic ReFerm® versus standard nutritional support in advanced alcohol-related liver disease (GALA-POSTBIO): a randomized controlled phase 2 trial.Nature communications · 2025Trial
- Diet and microbiome shape small-molecule cytokinin pools in mammals.Gut microbes · 2026Article
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- "Quadrupling" the protein family space with global metagenomics.Nucleic acids research · 2026Article
- The Biotechnological Applications of Marine Bacteria.Biology · 2026Review
- Global microbial DNA signatures of temperature and nutrient limitation across ecosystems.Nature microbiology · 2026Article
- Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects.iMeta · 2026Review
- The microbial unknome, a repertoire for microbial chatting?Heredity · 2026Review
- Alcohol-related liver disease disrupts bile acid homeostasis and gut microbial bile acid metabolism.JHEP reports : innovation in hepatology · 2026Article
- Structural mining and engineering of metagenome-derived Cas12a orthologs expands the CRISPR genome editing and multiplex diagnostics toolkit.Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Moving from a taxonomic to a functional perspective in global microbiome analysis requires optimizing multiplexing ratios.mSystems · 2026Article
- Cayman enables large-scale analysis of gut microbiome carbohydrate-active enzyme repertoires.Nature microbiology · 2026Article
- microntology: a lightweight, data-driven controlled vocabulary to describe earth's microbial habitats.Bioinformatics (Oxford, England) · 2026Article
- Host genetics shapes the recovery of the gut microbiome after antibiotic treatment: the role of the blood group relatedmSystems · 2026Article
- Defining metabolic niches for marine microbial heterotrophs.Science advances · 2026Article
- Microbial landscapes in dairy cow diseases: from localized dysbiosis to inter-organ axes.NPJ biofilms and microbiomes · 2026Review
- Clustering the protein universe of life using DIAMOND DeepClust.Nature methods · 2026Article
- Cooperation and the evolution of bacterial niche breadth.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
73 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 11 institutions in 8 countries.
Luis Pedro CoelhoInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China. coelho@fudan.edu.cn.ORCID http://orcid.org/0000-0002-9280-7885
Renato AlvesStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-7212-0234
Álvaro Rodríguez Del RíoCentro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM) - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, Spain.ORCID http://orcid.org/0000-0003-3907-3904
Pernille Neve MyersDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID http://orcid.org/0000-0002-1824-3305
Carlos P CantalapiedraCentro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM) - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, Spain.ORCID http://orcid.org/0000-0001-5263-533X
Joaquín Giner-LamiaCentro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM) - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, Spain.ORCID http://orcid.org/0000-0003-1553-8295
Thomas Sebastian SchmidtStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Daniel R MendeStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-6831-4557
Askarbek OrakovStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-6823-5269
Ivica Letunicbiobyte solutions GmbH, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-3560-4288
Falk HildebrandStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-0078-8948
Thea Van RossumStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Sofia K ForslundStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-4285-6993
Supriya KhedkarStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-6606-2202
Oleksandr M MaistrenkoStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-1961-7548
Shaojun PanInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-5270-5614
Longhao JiaInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China.
Pamela FerrettiStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-1707-9013
Shinichi SunagawaStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-3065-0314
Xing-Ming ZhaoInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China.
Henrik Bjørn NielsenClinical Microbiomics A/S, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-2281-5713
Jaime Huerta-CepasStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. j.huerta@csic.es.ORCID http://orcid.org/0000-0003-4195-5025
Peer BorkStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. bork@embl.de.ORCID http://orcid.org/0000-0002-2627-833X
European Molecular Biology Laboratory · DEFudan University · CNInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria · ESBiobyte Solutions (Germany) · DEClinical Microbiomics (Denmark) · DKMax Delbrück Center · DENorwich Research Park · GBSIB Swiss Institute of Bioinformatics · CHTechnical University of Denmark · DKUniversity of Hawaiʻi at Mānoa · USYonsei University · KR
Funding
Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10353Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10355European Research Council 669830
Abstract
Microbial genes encode the majority of the functional repertoire of life on earth. However, despite increasing efforts in metagenomic sequencing of various habitats
Indexed as
MetagenomeMetagenomicsAnti-Bacterial AgentsDrug Resistance, MicrobialEcosystemHumansAnti-Bacterial Agents
Identifiers
What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.