Evidence map›Paper›PMID 34911749›Full record

ArticleSexually transmitted infections2022

Mental health and implications for antiretroviral adherence in a multiethnic Asian cohort.

Jaspal Singh Dhaliwal, Lai Gwen Chan, Justine Chay Boon Goh, Karis Hui En Koh, Chen Seong Wong

Open access · hybridAbstract read
In one paragraph

Article in Sexually transmitted infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. [ART adherence and its association with depression, anxiety and stress].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Observational
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jaspal Singh DhaliwalPsychiatry, Tan Tock Seng Hospital, Singapore jaspal_singh@ttsh.com.sg.ORCID 0000-0002-5620-6038
Lai Gwen ChanPsychiatry, Tan Tock Seng Hospital, Singapore.ORCID 0000-0003-3553-1525
Justine Chay Boon GohPsychiatry, Tan Tock Seng Hospital, Singapore.ORCID 0000-0002-1008-4063
Karis Hui En KohPsychiatry, Tan Tock Seng Hospital, Singapore.ORCID 0000-0002-4346-0993
Chen Seong WongMedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0003-3127-2853
Tan Tock Seng Hospital · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesResearch suggests a high prevalence of depression and anxiety in people living with HIV, resulting in negative health outcomes and poorer help-seeking behaviours when undetected. Subsequent disease progression and non-adherence to treatment constitute a significant barrier to HIV treatment. This paper aims to identify the risk factors for the development of psychological distress and non-adherence to antiretroviral medication in people living with HIV.

methodsAn HIV outpatient clinical service screened for anxiety and depressive symptoms. As part of a retrospective analysis of the cohort, independent sample t-test and χ

resultsAfter adjusting for age, no history of alcohol use and psychiatric history were found to be significant risk factors for psychological distress during the programme. Older patients were less likely to be symptomatic during the programme. After adjusting for age, having received intervention and psychiatric history, significant risk factors for non-adherence to antiretroviral medication were mode of transmission, history of smoking and being symptomatic during the programme.

conclusionSignificant psychological distress occurring early in HIV care predicts future non-adherence to antiretroviral treatment, highlighting the importance of early detection and intervention for psychological distress in people living with HIV. Mental health interventions should be intercalated with treatment adherence interventions to improve HIV treatment outcomes.

Indexed as

HIV InfectionsMental HealthAnti-Retroviral AgentsHumansMedication AdherenceRetrospective StudiesAnti-Retroviral Agentsbehavioural sciencesHIVpsychiatrypsychologyrisk factors

Identifiers

PMID34911749
PMCPMC9613859
OpenAlexW4200443177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.