Evidence map›Paper›PMID 34911683›Full record

ArticleArchives of disease in childhood2022

Child mortality in England during the COVID-19 pandemic.

David Odd, Sylvia Stoianova, Tom Williams, Vicky Sleap, Peter Blair, Peter Fleming, Ingrid Wolfe, Karen Luyt

Abstract read
In one paragraph

Article in Archives of disease in childhood, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  9. [Pediatrics up to date-Brief notes on research].Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde · 2023
    Article
  10. Article
  11. Article
  12. COVID in Pediatric Age: an opinion paper.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  13. Article
  14. Article
  15. The Effect of COVID-19 on Pediatric Traumatic Orthopaedic Injuries: A Database Study.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David OddNational Child Mortality Database, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0002-6416-4966
Sylvia StoianovaNational Child Mortality Database, Bristol Medical School, University of Bristol, Bristol, UK.
Tom WilliamsNational Child Mortality Database, Bristol Medical School, University of Bristol, Bristol, UK.
Vicky SleapNational Child Mortality Database, Bristol Medical School, University of Bristol, Bristol, UK.
Peter BlairNational Child Mortality Database, Bristol Medical School, University of Bristol, Bristol, UK.
Peter FlemingNational Child Mortality Database, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0003-2521-5764
Ingrid WolfeSchool of Life Course Sciences, Department of Women and Children's Health, King's College London, London, UK.
Karen LuytNational Child Mortality Database, Bristol Medical School, University of Bristol, Bristol, UK karen.luyt@bristol.ac.uk.ORCID 0000-0002-9806-1092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesUsing the National Child Mortality Database (NCMD), this work aims to investigate and quantify the characteristics of children dying of COVID-19, and to identify any changes in rate of childhood mortality during the pandemic.

designWe compared the characteristics of the children who died in 2020, split by SARS-CoV-2 status. A negative binomial regression model was used to compare mortality rates in lockdown (23 March-28 June), with those children who died in the preceding period (6 January-22 March), as well as a comparable period in 2019.

settingEngland.

participantsChildren (0-17 years).

main outcome measuresCharacteristics and number of the children who died in 2020, split by SARS-CoV-2 status.

results1550 deaths of children between 6th of January and 28 June 2020 were notified to the NCMD; 437 of the deaths were linked to SARS-CoV-2 virology records, 25 (5.7%) had a positive PCR result. PCR-positive children were less likely to be white (37.5% vs 69.4%, p=0.003) and were older (12.2 vs 0.7 years, p<0.0006) compared with child deaths without evidence of the virus. All-cause mortality rates were similar during lockdown compared with both the period before lockdown in 2020 (rate ratio (RR) 0.93 (0.84 to 1.02)) and a similar period in 2019 (RR 1.02 (0.92 to 1.13)).

conclusionsThere is little to suggest that there has been excess mortality during the period of lockdown. The apparent higher frequency of SARS-CoV-2-positive tests among children from black, Asian and minority ethnic groups is consistent with findings in adults. Ongoing surveillance is essential as the pandemic continues.

Indexed as

EpidemicsSARS-CoV-2AdolescentChildChild MortalityChild, PreschoolCOVID-19EnglandFemaleHumansInfantInfant, NewbornMaleQuarantineCovid-19epidemiologymortality

Identifiers

PMID34911683
PMCPMC8219479

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.