Evidence map›Paper›PMID 34911191›Full record

ArticleNeuroImage. Clinical2021

Microstructural alterations of the corticospinal tract are associated with poor motor function in patients with severe congenital heart disease.

Melanie Ehrler, Michael von Rhein, Ladina Schlosser, Peter Brugger, Matthias Greutmann, Oliver Kretschmar, Beatrice Latal, Ruth Tuura O'Gorman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Melanie EhrlerChild Development Center, University Children's Hospital Zurich, Switzerland; Children's Research Center, University Children's Hospital Zurich, Switzerland; University of Zurich, Switzerland.
Michael von RheinChild Development Center, University Children's Hospital Zurich, Switzerland; Children's Research Center, University Children's Hospital Zurich, Switzerland.
Ladina SchlosserChild Development Center, University Children's Hospital Zurich, Switzerland; University of Zurich, Switzerland; Department of Neurology, University Hospital Zurich, Switzerland.
Peter BruggerDepartment of Psychiatry, University Hospital Zurich, Zurich, Switzerland; Rehabilitation Center Valens, Valens, Switzerland.
Matthias GreutmannUniversity Heart Center, Department of Cardiology, University of Zurich, Switzerland.
Oliver KretschmarUniversity of Zurich, Switzerland; Pediatric Cardiology, Pediatric Heart Center, University Children's Hospital Zurich, Switzerland.
Beatrice LatalChild Development Center, University Children's Hospital Zurich, Switzerland; Children's Research Center, University Children's Hospital Zurich, Switzerland; University of Zurich, Switzerland.
Ruth Tuura O'GormanChildren's Research Center, University Children's Hospital Zurich, Switzerland; Center for MR Research, University Children's Hospital Zurich, Switzerland. Electronic address: ruth.tuura@kispi.uzh.ch.
University Children's Hospital Zurich · CHUniversity of Zurich · CHUniversity Hospital of Zurich · CHValens Clinics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital heart disease (CHD) patients are at risk for neurodevelopmental impairments, including altered motor function. However, little is known about the neuroanatomical correlates of persistent motor deficits in CHD. Thus, we examined the link between corticospinal tract (CST) microstructure and motor function in adolescent and adult CHD patients compared to healthy controls. This study investigated 89 CHD patients (N

Indexed as

Heart Defects, CongenitalWhite MatterAdolescentAdultAnisotropyDiffusion Tensor ImagingHumansPyramidal TractsYoung AdultCongenital heart diseaseCorticospinal tractDiffusion tensor imagingMotor functionNeurodevelopmentWhite matter microstructure

Identifiers

PMID34911191
PMCPMC8628013
OpenAlexW3215147206

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.