ArticleJournal of medical virology2022
A rare case of drug-induced bradycardia associated with the just low dose use of methylprednisolone in a child with COVID-19.
Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Methylprednisolone-Induced Delayed and Sustained Bradycardia in Multisystem Inflammatory Syndrome in Children.Cureus · 2026Article
- Looking to the Past to Improve the Future: A Narrative Review of Lessons Learned from Inpatient Cardiac Arrest Care During the COVID-19 Pandemic.The Brown journal of hospital medicine · 2023Article
- A rare case of drug-induced bradycardia associated with the just low dose use of methylprednisolone in a child with COVID-19.Journal of medical virology · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Methylprednisolone (MP) is usually used to reduce inflammation reaction and tissue damage, which may have a beneficial treatment effect on coronavirus disease 2019 (COVID-19). However, we present the case of a child who manifests significant bradycardia with the use of just low dose MP on the premise of the long-term use of arbidol. Arbidol can affect the activity of CYP3A4, which is also a key metabolic enzyme of MP by competitive inhibition, and which is easy to aggravate the side effects of MP. Therefore, more attention should be paid to bradycardia occurrence in the patient with COVID-19 when MP is considered in COVID-19.
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