Evidence map›Paper›PMID 34910966›Full record

ArticlePsychiatry research2022

Associations between psychiatric morbidity and COVID-19 vaccine hesitancy: An analysis of electronic health records and patient survey.

Mara Eyllon, Alexander P Dang, J Ben Barnes, John Buresh, Gabrielle D Peloquin, Annika C Hogan, Scott T Shimotsu, Susan R Sama, Samuel S Nordberg

Open access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

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  17. Associations between Tobacco Use, Surges, and Vaccination Status over Time in the COVID-19 Era.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mara EyllonPractice Research Network, Reliant Medical Group, Worcester, MA, United States. Electronic address: mara.eyllon@reliantmedicalgroup.org.
Alexander P DangOptumLabs, UnitedHealth Group, Minneapolis, Minnesota, United States.
J Ben BarnesPractice Research Network, Reliant Medical Group, Worcester, MA, United States; Department of Psychiatry, University of Massachusetts Chan Medical School.
John BureshOptumLabs, UnitedHealth Group, Minneapolis, Minnesota, United States.
Gabrielle D PeloquinPractice Research Network, Reliant Medical Group, Worcester, MA, United States.
Annika C HoganPractice Research Network, Reliant Medical Group, Worcester, MA, United States.
Scott T ShimotsuOptumLabs, UnitedHealth Group, Minneapolis, Minnesota, United States.
Susan R SamaPractice Research Network, Reliant Medical Group, Worcester, MA, United States; Department of Public Health, University of Massachusetts, Lowell, Lowell, MA, United States.
Samuel S NordbergPractice Research Network, Reliant Medical Group, Worcester, MA, United States; Behavioral Health Department, Reliant Medical Group, Worcester, MA, United States.
Reliant Medical Group · USUnitedHealth Group (United States) · USResearch Network (United States) · USUniversity of Massachusetts Chan Medical School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychiatric illness confers significant risk for severe COVID-19 morbidity and mortality; identifying psychiatric risk factors for vaccine hesitancy is critical to mitigating risk in this population. This study examined the prevalence of vaccine hesitancy among those with psychiatric illness and the associations between psychiatric morbidity and vaccine hesitancy. Data came from electronic health records and a patient survey obtained from 14,365 patients at a group medical practice between February and May 2021. Logistic regression was used to calculate odds for vaccine hesitancy adjusted for sociodemographic characteristics and physical comorbidity. Of 14,365 participants 1,761 (12.3%) participants reported vaccine hesitancy. Vaccine hesitancy was significantly more prevalent among participants with substance use (29.6%), attention deficit and hyperactivity (23.3%), posttraumatic stress (23.1%), bipolar (18.0%), generalized anxiety (16.5%), major depressive (16.1%), and other anxiety (15.5%) disorders, tobacco use (18.6%), and those previously infected with COVID-19 (19.8%) compared to participants without . After adjusting for sociodemographic characteristics and physical comorbidities, substance use disorders and tobacco use were significantly associated with increased odds for vaccine hesitancy and bipolar disorder was significantly inversely associated with vaccine hesitancy. Interventions to improve uptake in these populations may be warranted.

Indexed as

COVID-19Major Depressive DisorderCOVID-19 VaccinesCross-Sectional StudiesElectronic Health RecordsHumansPrevalenceSARS-CoV-2Vaccination HesitancyCOVID-19 VaccinesCOVID-19Psychiatric illnessVaccine hesitancy

Identifiers

PMID34910966
PMCPMC8648380
OpenAlexW4200000057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.