ArticlePloS one2021
National Early Warning Score 2 (NEWS2) to predict poor outcome in hospitalised COVID-19 patients in India.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Applications of the Early Warning Score as an outcome measure: a systematic review of methodologies.BMJ health & care informatics · 2026Pooled it
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- A novel deterioration prediction system for mild COVID-19 patients in Korea: a retrospective study.Scientific reports · 2024Article
- Predictors of mortality among inpatients in COVID-19 treatment centers in the city of Butembo, North Kivu, Democratic Republic of Congo.PLOS global public health · 2024Article
- Performance of point-of-care severity scores to predict prognosis in patients admitted through the emergency department with COVID-19.Journal of hospital medicine · 2023Article
- Reduction in the COVID-19 pneumonia case fatality rate by silver nanoparticles: A randomized case study.Heliyon · 2023Article
- [COVID-19 mortality prediction. Comparison between two scales].Revista medica del Instituto Mexicano del Seguro Social · 2022Article
- A randomized, placebo controlled, double blinded, parallel group clinical study to evaluate the efficacy and safety of AEV01 along with standard care for elderly patients with mild COVID-19.Journal of Ayurveda and integrative medicineArticle
- Early Clinical Deterioration Risk Assessment in Inpatient Units of a Public University Hospital.Iranian journal of nursing and midwifery researchArticle
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5 authors at 1 institution in 1 country.
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Abstract
backgroundWhile several parameters have emerged as predictors of prognosis of COVID-19, a simple clinical score at baseline might help early risk stratification. We determined the ability of National Early Warning Score 2 (NEWS2) to predict poor outcomes among adults with COVID-19.
methodsA prospective study was conducted on 399 hospitalised adults with confirmed SARS-CoV-2 infection between August and December 2020. Baseline NEWS2 score was determined. Primary outcome was poor outcomes defined as need for mechanical ventilation or death within 28 days. The sensitivity, specificity and Area under the curve were determined for NEWS2 scores of 5 and 6.
resultsMean age of patients was 55.5 ± 14.8 years and 275 of 399 (68.9%) were male. Overall mortality was 3.8% and 7.5% had poor outcomes. Median (interquartile range) NEWS2 score at admission was 2 (0-6). Sensitivity and specificity of NEWS 2 of 5 or more in predicting poor outcomes was 93.3% (95% CI: 76.5-98.8) and 70.7% (95% CI: 65.7-75.3) respectively [area under curve 0.88 (95% CI: 0.847-0.927)]. Age, baseline pulse rate, baseline oxygen saturation, need for supplemental oxygen and ARDS on chest X ray were independently associated with poor outcomes.
conclusionsNEWS2 score of 5 or more at admission predicts poor outcomes in patients with COVID-19 with good sensitivity and can easily be applied for risk stratification at baseline. Further studies are needed in the Indian setting to validate this simple score and recommend widespread use.
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