ArticlePloS one2021
Upper limb rehabilitation system based on virtual reality for breast cancer patients: Development and usability study.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- OncoVR - Virtual Reality in Oncology for Patient-centered Care: A Systematic Review and Meta-Analysis.Current oncology reports · 2026Pooled it
- Opportunities and challenges of virtual reality-based interventions for patients with breast cancer: a systematic review.BMC medical informatics and decision making · 2023Pooled it
- Extended reality in supporting cancer patients and survivors: A systematic review on the benefits and challenges across the cancer care continuum.Future healthcare journal · 2026Review
- Exploring Usability and User Engagement in Fully Immersive Virtual Reality Systems for Upper Limb Stroke Rehabilitation: A Scoping Review.Progress in rehabilitation medicine · 2026Review
- The role of virtual reality in breast cancer survivors: A scoping review.Preventive medicine reports · 2025Article
- The effects of the generative adversarial network and personalized virtual reality platform in improving frailty among the elderly.Scientific reports · 2025Article
- Impact of Physical Exercise on Breast Cancer-Related Lymphedema and Non-Invasive Measurement Tools: A Systematic Review.Cancers · 2025Review
- A comprehensive perspective of the innovation and reflection on virtual reality in the teaching and learning of anesthesiology.Frontiers in medicine · 2025Review
- Clinical Feasibility of Applying Immersive Virtual Reality during Robot-Assisted Gait Training for Individuals with Neurological Diseases: A Pilot Study.Brain sciences · 2024Article
- Telemedicine Applications for Cancer Rehabilitation: Scoping Review.JMIR cancer · 2024Article
- Application of immersive virtual reality in the training of wheelchair boxers: evaluation of exercise intensity and users experience additional load- a pilot exploratory study.BMC sports science, medicine & rehabilitation · 2024Article
- Virtual Reality-Based Exercise Rehabilitation in Cancer-Related Dysfunctions: Scoping Review.Journal of medical Internet research · 2024Article
- A Cross-Sectional Study Using STROBE Platform to Examine Sleep Characteristics, Mental Health and Academic Performance of Female Applied Medical Sciences Students in the Southwest of Saudi Arabia.Behavioral sciences (Basel, Switzerland) · 2023Article
- Experience of using a virtual reality rehabilitation management platform for breast cancer patients: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Using virtual reality to prepare patients for radiotherapy: A systematic review of interventional studies with educational sessions.Technical innovations & patient support in radiation oncology · 2023Review
- Effect of a telehealth-based exercise intervention on the physical activity of patients with breast cancer: A systematic review and meta-analysis.Asia-Pacific journal of oncology nursing · 2022Review
- The effect of digital acupressure on chemotherapy-induced nausea in Indonesian patients with stages III-IV breast cancer.Journal of Ayurveda and integrative medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFunctional exercise is crucial for breast cancer patients after surgery, and the use of virtual reality technology to assist patients with postoperative upper limb functional rehabilitation has gradually attracted the attention of researchers. However, the usability of the developed rehabilitation system is still unknown to a large extent. The purpose of this study was to develop a virtual reality upper limb rehabilitation system for patients after breast cancer surgery and to explore its usability.
methodsWe built a multidisciplinary team based on virtual reality and human-computer interaction technology and designed and developed an upper limb function rehabilitation system for breast cancer patients after surgery. Breast cancer patients were recruited from a grade III-a general hospital in Changchun city for the experiment. We used the System Usability Scale to evaluate the system availability, the Presence Questionnaire scale to measure the immersive virtual reality scene, and the Simulator Sickness Questionnaire subjective measurement scale for simulator sickness symptoms.
resultsThis upper limb rehabilitation system hardware consisted of Head-mounted Display, a control handle and notebook computers. The software consisted of rehabilitation exercises and game modules. A total of 15 patients were tested on this system, all of whom were female. The mean age was 54.73±7.78 years, and no patients were excluded from the experiment because of adverse reactions such as dizziness and vomiting. The System Usability Scale score was 90.50±5.69, the Presence Questionnaire score was 113.40±9.58, the Simulator Sickness Questionnaire-nausea score was 0.93±1.16, the Simulator Sickness Questionnaire-oculomotor score was 0.80±1.27, the Simulator Sickness Questionnaire-disorientation score was 0.80±1.27, and the Simulator Sickness Questionnaire total score was 2.53±3.40.
conclusionsThis study fills in the blanks regarding the upper limb rehabilitation of breast cancer patients based on virtual reality technology system usability research. As the starting point of research in the future, we will improve the system's function and design strictly randomized controlled trials, using larger samples in the promotion, to evaluate its application in breast cancer patients with upper limbs and other physiological functions and the feasibility and effects of rehabilitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.