ArticlePLoS neglected tropical diseases2021
Culicoides Latreille (Diptera: Ceratopogonidae) as potential vectors for Leishmania martiniquensis and Trypanosoma sp. in northern Thailand.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 43 citations in OpenAlex.
- Article
- Miltefosine and emerging Leishmania (Mundinia) in Southeast Asia: Molecular insights, therapeutic challenges, and future strategic implementation.PLoS neglected tropical diseases · 2026Review
- Integrative morphological and DNA barcoding analysis of Forcipomyia (Lasiohelea) midges: cryptic diversity and first molecular detection of multiple Leishmania species in a leishmaniasis-endemic focus in Southern Thailand.Parasites & vectors · 2026Article
- Diversity and Host Blood Meal Analysis ofInsects · 2026Article
- First experimental assessment of Phlebotomus mascittii vector competence for Leishmania infantum and Leishmania martiniquensis.Parasites & vectors · 2026Article
- Molecular identification and characterization ofCurrent research in parasitology & vector-borne diseases · 2026Article
- Pathogen surveillance in cave-dwelling phlebotomine sand flies from Chiang Rai, northern Thailand, with the first detection ofCurrent research in parasitology & vector-borne diseases · 2026Article
- Autochthonous canine cutaneous leishmaniasis caused byCurrent research in parasitology & vector-borne diseases · 2026Article
- Prevalence, morphology, and molecular characterization of trypanosomes in bulbuls from Thailand.Parasite (Paris, France) · 2026Article
- Emergence of Autochthonous Leishmania (Mundinia) martiniquensis Infections in Horses, Czech Republic and Austria, 2019-2023.Emerging infectious diseases · 2025Article
- First record of mermithid parasitism in adult biting midges, Culicoides huffi (Diptera: Ceratopogonidae), collected from Southern Thailand, with ultrastructural and molecular characterization.Parasites & vectors · 2025Article
- DNA barcoding of Culicoides biting midges (Diptera: Ceratopogonidae) and detection of Leishmania and other trypanosomatids in southern Thailand.Parasites & vectors · 2025Article
- A preliminary account of Culicoides (Diptera: Ceratopogonidae) from the Andaman and Nicobar Islands with 13 new records and updated species inventory from India.Parasites & vectors · 2025Article
- Molecular detection of parasites and host preference in wild-caught Culicoides biting midges (Diptera: Ceratopogonidae) in Chiang Mai and Nakhon Si Thammarat Provinces, Thailand.Parasite (Paris, France) · 2025Article
- Improvements in Blood Profiles of Canines Naturally Infected with Triple Blood Pathogens (Animals : an open access journal from MDPI · 2024Article
- Cave-dwelling phlebotomine sand flies (Diptera: Psychodidae: Phlebotominae) in Thailand: population composition and pathogen detection of Bartonella and Trypanosoma.Parasites & vectors · 2024Article
- Review
- An update onParasite epidemiology and control · 2024Review
- The development of L. major, L. donovani and L. martiniquensis, Leishmania currently emerging in Europe, in the sand fly species Phlebotomus perniciosus and P. tobbi.PLoS neglected tropical diseases · 2024Article
- Seasonal dynamics, Leishmania diversity, and nanopore-based metabarcoding of blood meal origins in Culicoides spp. in the newly emerging focus of leishmaniasis in Northern Thailand.Parasites & vectors · 2024Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biting midges of genus Culicoides (Diptera: Ceratopogonidae) are the vectors of several pathogenic arboviruses and parasites of humans and animals. Several reports have suggested that biting midges might be a potential vector of Leishmania parasites. In this study, we screened for Leishmania and Trypanosoma DNA in biting midges collected from near the home of a leishmaniasis patient in Lamphun province, northern Thailand by using UV-CDC light traps. The identification of biting midge species was based on morphological characters and confirmed using the Cytochrome C oxidase subunit I (COI) gene. The detection of Leishmania and Trypanosoma DNA was performed by amplifying the internal transcribed spacer 1 (ITS1) and small subunit ribosomal RNA (SSU rRNA) genes, respectively. All the amplified PCR amplicons were cloned and sequenced. The collected 223 biting midges belonged to seven species (Culicoides mahasarakhamense, C. guttifer, C. innoxius, C. sumatrae, C. huffi, C. oxystoma, and C. palpifer). The dominant species found in this study was C. mahasarakhamense (47.53%). Leishmania martiniquensis DNA was detected in three samples of 106 specimens of C. mahasarakhamense tested indicating a field infection rate of 2.83%, which is comparable to reported rates in local phlebotomines. Moreover, we also detected Trypanosoma sp. DNA in one sample of C. huffi. To our knowledge, this is the first molecular detection of L. martiniquensis in C. mahasarakhamense as well as the first detection of avian Trypanosoma in C. huffi. Blood meal analysis of engorged specimens of C. mahasarakhamense, C. guttifer, and C. huffi revealed that all specimens had fed on avian, however, further studies of the host ranges of Culicoides are needed to gain a better insight of potential vectors of emerging leishmaniasis. Clarification of the vectors of these parasites is also important to provide tools to establish effective disease prevention and control programs in Thailand.
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