Evidence map›Paper›PMID 34910613›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Effect of Marital Status on the Survival of Patients With Adenocarcinoma of the Esophagogastric Junction: A Population-Based, Propensity-Matched Study.

Sihan Wang, Liubo Chen, Dongdong Chen, Jian Chao, Yangliu Shao, Kejun Tang, Wenteng Chen

Open access · goldAbstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Sihan WangCancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences), the Second Affiliated Hospital, 89681Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Liubo ChenDepartment of Colorectal Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, the Second Affiliated Hospital, 89681Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-5582-7203
Dongdong ChenCancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences), the Second Affiliated Hospital, 89681Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Jian ChaoDepartment of Electrocardigram, Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang, China.
Yangliu ShaoDepartment of Hematology, 104607Chinese PLA General Hospital, Beijing, China.
Kejun TangDepartment of Surgery, Women's Hospital, School of Medicine, 89681Zhejiang University, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-9461-3646
Wenteng ChenCollege of Pharmaceutical Sciences, 366096Zhejiang University, Hangzhou, Zhejiang, China.
Zhejiang University · CNChinese PLA General Hospital · CNNingbo Medical Center Lihuili Hospital · CNWomen's Hospital, School of Medicine, Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMarital status has been reported as an independent prognostic factor in various types of malignancies. However, the association between marital status and outcomes of patients with adenocarcinoma of the esophagogastric junction (AEG) has not been fully explored. To this end, we aimed to investigate the effect of marital status on survival of AGE patients.

methodsThe Surveillance Epidemiology and End Results (SEER) database (2010-2015) was used to extract eligible patients with Siewert type II AEG. Meanwhile, propensity score matching was performed to match 1576 unmarried patients with 1576 married patients. Kaplan-Meier method with log-rank test was used to plot survival curves, univariate and multivariate Cox regression analyses were adopted to investigate the association of marital status with overall survival (OS) and cancer-specific survival (CSS) in AEG patients before and after matching.

resultsMultivariate analysis in the unmatched cohort revealed that marital status was an independent prognostic factor in patients with Siewert type II AEG. Unmarried patients had poorer OS (hazard ratio [HR]: 1.22, 95% confidence interval [CI]: 1.12-1.29,

conclusionsThis population-based study identified that marital status was an independent prognostic indicator for AEG patients. Married AEG patients had better prognosis than their unmarried counterparts.

Indexed as

AdenocarcinomaAgedEsophageal NeoplasmsEsophagogastric JunctionFemaleHumansKaplan-Meier EstimateMaleMarital StatusMiddle AgedMultivariate AnalysisPrognosisPropensity ScoreProportional Hazards ModelsRisk FactorsSEER Programadenocarcinoma of the esophagogastric junctionmarital statusprognosisSEER

Identifiers

PMID34910613
PMCPMC8689606
OpenAlexW4200408775

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.