Evidence map›Paper›PMID 34910376›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Magnetophoretic Micro-Distributor for Controlled Clustering of Cells.

Jonghwan Yoon, Yumin Kang, Hyeonseol Kim, Sri Ramulu Torati, Keonmok Kim, Byeonghwa Lim, CheolGi Kim

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Magnetophoretic Micro-Distributor for Controlled Clustering of Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonghwan YoonDepartment of Emerging Materials Science, DGIST, Daegu, 42988, Republic of Korea.ORCID 0000-0002-0855-859X
Yumin KangDepartment of Emerging Materials Science, DGIST, Daegu, 42988, Republic of Korea.ORCID 0000-0002-1274-9815
Hyeonseol KimDepartment of Emerging Materials Science, DGIST, Daegu, 42988, Republic of Korea.ORCID 0000-0002-7007-5150
Sri Ramulu ToratiDepartment of Emerging Materials Science, DGIST, Daegu, 42988, Republic of Korea.ORCID 0000-0001-6571-1653
Keonmok KimDepartment of Emerging Materials Science, DGIST, Daegu, 42988, Republic of Korea.ORCID 0000-0002-9698-3755
Byeonghwa LimDepartment of Emerging Materials Science, DGIST, Daegu, 42988, Republic of Korea.ORCID 0000-0001-9659-1105
CheolGi KimDepartment of Emerging Materials Science, DGIST, Daegu, 42988, Republic of Korea.ORCID 0000-0001-9531-5758

Funding

Korea government (MSIT) 2018R1A5A1025511National Research Foundation of Korea
6 · The paper itself

Abstract

Cell clustering techniques are important to produce artificial cell clusters for in vitro models of intercellular mechanisms at the single-cell level. The analyses considering physical variables such as the shape and size of cells have been very limited. In addition, the precise manipulation of cells and control of the physical variables are still challenging. In this paper, a magnetophoretic device consisting of a trampoline micromagnet and active elements that enable the control of individual selective jumping motion and positioning of a micro-object is proposed. Based on a numerical simulation under various conditions, automatic separation or selective clustering of micro-objects according to their sizes is performed by parallel control and programmable manipulation. This method provides efficient control of the physical variables of cells and grouping of cells with the desired size and number, which can be a milestone for a better understanding of the intercellular dynamics between clustered cells at the single-cell level for future cell-on-chip applications.

Indexed as

Lab-On-A-Chip DevicesCell MovementCluster AnalysisComputer SimulationImmunomagnetic SeparationMagneticscell-cell interactioncell clusteringlab-on-a-chipmagnetophoresissingle-cell manipulation

Identifiers

PMID34910376
PMCPMC8867205

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.