Evidence map›Paper›PMID 34910285›Full record

ArticleJournal of clinical monitoring and computing2022

A comparison of endotracheal tube compensation techniques for the measurement of respiratory mechanical impedance at low frequencies.

Andrea F Cruz, Jacob Herrmann, Carlos R R Carvalho, David W Kaczka

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Journal of clinical monitoring and computing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Andrea F CruzLaboratorio de Pneumologia LIM-09, Disciplina de Pneumologia, Heart Institute (Incor), Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.ORCID 0000-0001-6969-1223
Jacob HerrmannDepartment of Anesthesia, University of Iowa, Iowa City, IA, USA.ORCID 0000-0001-5046-5592
Carlos R R CarvalhoLaboratorio de Pneumologia LIM-09, Disciplina de Pneumologia, Heart Institute (Incor), Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.ORCID 0000-0002-1618-8509
David W KaczkaDepartment of Anesthesia, University of Iowa, Iowa City, IA, USA. david-kaczka@uiowa.edu.ORCID 0000-0003-4378-5242
University of Iowa · USHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

Device for Multi-Frequency Oscillatory Ventilation in Adult Patients with the Acute Respiratory Distress SyndromeR41HL140640 · NHLBI · OSCILLAVENT, INC. · PI KACZKA, DAVID W. · 2018 to 2018
$225k
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001NHLBI NIH HHS R41 HL140640U.S. Department of Defense W81XWH-16-1-0434U.S. Department of Defense W81XWH-20-1-0696U.S. Department of Defense W81XWH-21-1-0507
6 · The paper itself

Abstract

Measurement of respiratory impedance ([Formula: see text]) in intubated patients requires accurate compensation for pressure losses across the endotracheal tube (ETT). In this study, we compared time-domain (TD), frequency-domain (FD) and combined time-/frequency-domain (FT) methods for ETT compensation. We measured total impedance ([Formula: see text]) of a test lung in series with three different ETT sizes, as well as in three intubated porcine subjects. Pressure measurement at the distal end of the ETT was used to determine the true [Formula: see text]. For TD compensation, pressure distal to the ETT was obtained based on its resistive and inertial properties, and the corresponding [Formula: see text] was estimated. For FD compensation, impedance of the isolated ETT was obtained from oscillatory flow and pressure waveforms, and then subtracted from [Formula: see text]. For TF compensation, the nonlinear resistive properties of the ETT were subtracted from the proximal pressure measurement, from which the linear resistive and inertial ETT properties were removed in the frequency-domain to obtain [Formula: see text]. The relative root mean square error between the actual and estimated [Formula: see text] ([Formula: see text]) showed that TD compensation yielded the least accurate estimates of [Formula: see text] for the in vitro experiments, with small deviations observed at higher frequencies. The FD and TF compensations yielded estimates of [Formula: see text] with similar accuracies. For the porcine subjects, no significant differences were observed in [Formula: see text] across compensation methods. FD and TF compensation of the ETT may allow for accurate oscillometric estimates of [Formula: see text] in intubated subjects, while avoiding the difficulties associated with direct tracheal pressure measurement.

Indexed as

Intubation, IntratrachealTracheaAnimalsElectric ImpedanceHumansOscillometryRespiratory RateSwineEndotracheal tubeForced oscillation techniqueMechanical impedanceMechanical ventilationOscillometry

Identifiers

PMID34910285
PMCPMC9198108
OpenAlexW4200008341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.