Evidence map›Paper›PMID 34910276›Full record

ReviewCurrent HIV/AIDS reports2021

Introducing the Dapivirine Vaginal Ring in Sub-Saharan Africa: What Can We Learn from Oral PrEP?

Neeraja Bhavaraju, Kathleen Shears, Katie Schwartz, Saiqa Mullick, Patriciah Jeckonia, Joseph Murungu, Udita Persaud, Ashley Vij, Kristine Torjesen

Abstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Neeraja Bhavaraju, Afton Bloom, 123 Meserole Avenue, Brooklyn, NY, 11222, USA.
Kathleen Shears, FHI 360, 1825 Connecticut Avenue NW, Washington, DC, 20009, USA. kshears@fhi360.org.ORCID 0000-0002-4922-6540
Katie Schwartz, FHI 360, 359 Blackwell Street, Durham, NC, 27701, USA.
Saiqa MullickWits Reproductive Health and HIV Institute, 8 Blackwood Avenue, Parktown, Johannesburg, South Africa.
Patriciah JeckoniaLVCT Health, Batian Lane, Off Argwings Kodhek Road, Hurlingam, Nairobi, Kenya.
Joseph MurunguPangaea Zimbabwe AIDS Trust, 27 Rowland Square, Milton Park, Harare, Zimbabwe.
Udita PersaudUnited States Agency for International Development, 1300 Pennsylvania Avenue NW, Washington, DC, 20523, USA.
Ashley VijUnited States Agency for International Development, 1300 Pennsylvania Avenue NW, Washington, DC, 20523, USA.
Kristine Torjesen, FHI 360, 359 Blackwell Street, Durham, NC, 27701, USA.

Funding

PEPFARUnited States Agency for International Development AID-OAA-A-15-00045
6 · The paper itself

Abstract

purpose of reviewClinical trials have found that the dapivirine vaginal ring (DVR) is safe to use and effective at reducing women's risk of acquiring HIV infection. As countries prepare for the introduction of this novel long-acting, woman-controlled prevention method, an examination of key learnings from oral pre-exposure prophylaxis (PrEP) delivery will help programs leverage successful innovations and approaches to support DVR scale-up and expand the method mix for HIV prevention. RECENT

findingsIntensive efforts over the past 5 years have yielded lessons on how to facilitate access to oral PrEP; expand service delivery for PrEP; address the knowledge, attitudes, and skills providers need to support PrEP initiation and effective use; develop messaging that builds community and partner support and combats stigma; and understand the cyclical nature of PrEP use. Evidence from oral PrEP introduction and scale-up can help inform and expedite DVR introduction.

Indexed as

Anti-HIV AgentsContraceptive Devices, FemaleHIV InfectionsPre-Exposure ProphylaxisAfrica South of the SaharaFemaleHumansPyrimidinesAnti-HIV AgentsDapivirinePyrimidinesAGYWDapivirine vaginal ringHIV preventionPre-exposure prophylaxisPrEPSub-Saharan Africa

Identifiers

PMID34910276
PMCPMC8671875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.