Evidence map›Paper›PMID 34910238›Full record

ArticleApplied microbiology and biotechnology2022

Production of galactosylated complex-type N-glycans in glycoengineered Saccharomyces cerevisiae.

Mari A Piirainen, Heidi Salminen, Alexander D Frey

Open access · hybridAbstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Protein N -Glycans in Healthy and Sclerotic Glomeruli in Diabetic Kidney Disease.Journal of the American Society of Nephrology : JASN · 2024
    Article
  6. EngineeringEngineering microbiology · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mari A Piirainen *Department of Bioproducts and Biosystems, Aalto University, Espoo, Finland.
Heidi Salminen *Department of Bioproducts and Biosystems, Aalto University, Espoo, Finland.
Alexander D FreyDepartment of Bioproducts and Biosystems, Aalto University, Espoo, Finland. alexander.frey@aalto.fi.ORCID http://orcid.org/0000-0002-4371-0227
Aalto University · FI

Funding

Biotieteiden ja Ympäristön Tutkimuksen Toimikunta 298476
6 · The paper itself

Abstract

N-glycosylation is an important posttranslational modification affecting the properties and quality of therapeutic proteins. Glycoengineering in yeast aims to produce proteins carrying human-compatible glycosylation, enabling the production of therapeutic proteins in yeasts. In this work, we demonstrate further development and characterization of a glycoengineering strategy in a Saccharomyces cerevisiae Δalg3 Δalg11 strain where a truncated Man

Indexed as

Saccharomyces cerevisiae ProteinsSchizosaccharomycesGlycosylationHumansPolysaccharidesSaccharomyces cerevisiaePolysaccharidesSaccharomyces cerevisiae ProteinsGalactosyltransferaseGlucosamineGlycoengineeringUDP-glucose 4-epimeraseYeast

Identifiers

PMID34910238
PMCPMC8720083
OpenAlexW4200538989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.