SynthesisClinical neuroradiology2022
Endovascular Treatment of Cavernous Sinus Dural Arteriovenous Fistulas. Institutional Series, Systematic Review and Meta-Analysis.
Synthesis in Clinical neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05729295 (Cerebral Vascular Malformations), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cerebral Vascular Malformations: From Multimodal Imaging, to Endovascular, Surgical or Combined Treatment.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Natural history and treatment of asymptomatic unruptured carotid cavernous aneurysms: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Endovascular treatment in bilateral cavernous sinus dural arteriovenous fistulas: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Article
- Endoscopic endonasal transsphenoidal management of an indirect cavernous sinus dural arteriovenous fistula: a case report.Acta neurochirurgica · 2026Article
- Evolving Management Paradigms in Dural Arteriovenous Fistulas: From Classification to Personalized Endovascular Therapy.Biomedicines · 2025Article
- Cavernous Sinus Dural Arteriovenous Fistula Initially Misdiagnosed As Ocular Myasthenia Gravis: A Case Report.Cureus · 2025Article
- A Practical Approach to Intracranial Dural Arteriovenous Fistulas: Pathogenesis, Classification and Management.Journal of clinical medicine · 2025Review
- Tortuous conjunctival vessels and central retinal vein occlusion in spontaneous dural arteriovenous fistula.Eye (London, England) · 2025Article
- Spontaneous Superior Ophthalmic Vein Thrombosis Resulted in Posterior Fossa Venous Congestion in a Case of Cavernous Sinus Dural Arteriovenous Fistula: Successful Treatment with Direct Interruption Surgery.NMC case report journal · 2025Article
- Microsurgical management of cranial dural arteriovenous fistulas: Treating the "Sheep in Wolf's clothing"? - Three decades of experience and lessons learned.Brain & spine · 2025Article
- Endovascular Treatment With Targeted Embolization of Cavernous Sinus Dural Arteriovenous Fistulas: A Single-Center Study.Korean journal of radiology · 2024Article
- Intracranial dural arteriovenous fistula: a comprehensive review of the history, management, and future prospective.Acta neurologica Belgica · 2023Review
- Cavernous sinus dural arteriovenous fistula treated with transvenous embolization through facial vein: A case report.Surgical neurology international · 2023Article
- Spontaneous complete regression of malignant cavernous sinus dural arteriovenous fistula following partial transarterial embolization with liquid embolic material: Report of two cases.Surgical neurology international · 2023Article
- Radiation Dose and Fluoroscopy Time of Endovascular Coil Embolization in Patients with Carotid Cavernous Fistulas.Diagnostics (Basel, Switzerland) · 2022Article
- Transfemoral trans-facial vein-superior ophthalmic vein to embolize cavernous sinus dural arteriovenous fistulas.Frontiers in neurology · 2022Review
- Intracranial dural arteriovenous fistulas with pial arterial supply: A narrative review.Brain circulationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeEndovascular treatment represents the first-line therapy for cavernous sinus dural arteriovenous fistulas (CS-dAVF); however, different approaches and embolic agents as well as occlusion rates, complications and clinical outcomes are reported among the published series. In this study we performed a comprehensive meta-analysis to investigate clinical and radiological outcomes after endovascular treatment of CS-dAVFs.
methodsPubMed, Ovid Medline, Ovid EMBASE, Scopus, and Web of Science were screened for a comprehensive literature review from 1990 to 2020 regarding series of patients treated for CS-dAVF with endovascular approaches. We performed a proportion meta-analysis estimating the pooled rates of each outcome also including data of patients treated in our center.
resultsA total of 22 studies reporting 1043 patients and 1066 procedures were included. Chemosis was reported in 559 out of 1043 patients (45.9%), proptosis in 498 (41.5%), and ophthalmoplegia in 344 (23.5%). A transvenous embolization was preferred in 753 cases (63.2%) and coils were used in 712 out of 1066 procedures (57.8%). Overall, 85% (95% confidence interval, CI 69.5-96.1%) of patients had a complete resolution of symptoms, while complications occurred in 7.75% (95% CI 3.82-12.7%) with minimal permanent deficits (0.15%). The mortality rate was 1 out of 1043 patients (< 0.001).
conclusionA transvenous coiling is the most common endovascular approach for CS-dAVF, achieving a high percentage of radiological and clinical resolution and low complication rates. Transvenous approaches show less complications than transarterial ones, and coils appear safer than liquid embolic agents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.