Evidence map›Paper›PMID 34910179›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2021

Building Global Capacity to Conduct Pathology-Based Postmortem Examination: Establishing a New Training Hub for Minimally Invasive Tissue Sampling.

Christina R Paganelli, Lindsay Parlberg, Norman J Goco, Jana M Ritter, Roosecelis B Martines, Sherif R Zaki, Edwin Walong, Washington Ochieng, Dennis Inyangala, Walter Barake and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Minimally Invasive Tissue Sampling Surveillance Alliance-Facilitating the Expansion of Pathology-Based Mortality Surveillance.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

Christina R PaganelliResearch Triangle Institute (RTI) International, Seattle, Washington, USA.ORCID 0000-0001-5453-1155
Lindsay ParlbergRTI International, Research Triangle Park, North Carolina, USA.
Norman J GocoRTI International, Research Triangle Park, North Carolina, USA.
Jana M RitterDivision of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Roosecelis B MartinesDivision of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Sherif R ZakiDivision of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Edwin WalongAnatomic Pathology Unit, Department of Human Pathology, School of Medicine, University of Nairobi, Nairobi, Kenya.
Washington OchiengAnatomic Pathology Unit, Department of Human Pathology, School of Medicine, University of Nairobi, Nairobi, Kenya.
Dennis InyangalaAnatomic Pathology Unit, Department of Human Pathology, School of Medicine, University of Nairobi, Nairobi, Kenya.
Walter BarakeAnatomic Pathology Unit, Department of Human Pathology, School of Medicine, University of Nairobi, Nairobi, Kenya.
Cyrus WachiuryFarewell Home Department, Kenyatta National Hospital, Kenya Laboratory Medicine Department, Nairobi, Kenya.
Natalia RakislovaISGlobal, Barcelona Institute for Global Health, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Lorena MarimonISGlobal, Barcelona Institute for Global Health, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Melania FerrandoISGlobal, Barcelona Institute for Global Health, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Jaume OrdiISGlobal, Barcelona Institute for Global Health, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Elizabeth McClureRTI International, Research Triangle Park, North Carolina, USA.
Barcelona Institute for Global Health · ESRTI International · USUniversity of Nairobi · KECenters for Disease Control and Prevention · USKenyatta National Hospital · KE

Funding

Bill and Melinda Gates Foundation OPP1180554
6 · The paper itself

Abstract

backgroundMinimally invasive tissue sampling (MITS), an alternative to complete diagnostic autopsy, is a pathology-based postmortem examination that has been validated in low- and middle-income countries (LMICs) and can provide accurate cause of death information when used with other data. The MITS Surveillance Alliance was established in 2017 with the goal to expand MITS globally by increasing training capacity, accessibility, and availability in LMICs. Between January 2019 and May 2020, the MITS Surveillance Alliance convened a multidisciplinary team of technical advisors to attain this goal.

methodsThis article describes the process used to develop criteria and identify an optimal location for a MITS training hub, establish a cadre of LMIC-based trainers, refine standardized MITS sample collection protocols, develop a training program, and release a telepathology platform for quality assessment of MITS histological samples.

resultsResults include the creation of a training hub and curriculum, with a total of 9 pathologists and technicians trained as part of the training of the trainers. Those trainers trained 15 participants from seven MITS projects representing 6 LMICs trained in MITS sample collection. The 15 participants have gone on to train more than 50 project-level staff in MITS sample collection.

conclusionsLessons learned include an appreciation for using an iterative process for establishing standardized procedures, creating opportunities for all stakeholders to deliver critical feedback, and highlighting the importance of complementing in-person trainings with ongoing technical assistance.

Indexed as

PovertyTelepathologyAutopsyCurriculumHumansSpecimen Handlingcapacity buildinglow- and middle-income countriesminimally invasive tissue samplingmortality surveillancetraining

Identifiers

PMID34910179
PMCPMC8672740
OpenAlexW4200544468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.