Evidence map›Paper›PMID 34910175›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2021

Factors Associated With Parental Acceptance of Minimally Invasive Tissue Sampling to Identify the Causes of Stillbirth and Neonatal Death.

Shiyam Sunder Tikmani, Sarah Saleem, Janet L Moore, Sayyeda Reza, Guruprasad Gowder, Sangappa Dhaded, S Yogesh Kumar, Shivaprasad S Goudar, Vardendra Kulkarni, Sunil Kumar and 4 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Minimally Invasive Tissue Sampling Surveillance Alliance-Facilitating the Expansion of Pathology-Based Mortality Surveillance.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Shiyam Sunder TikmaniDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Sarah SaleemDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Janet L MooreRTI International, Durham, North Carolina, USA.
Sayyeda RezaDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Guruprasad GowderJJM Medical College, Davengere, India.
Sangappa DhadedKLE Academy of Higher Education and Research's Jawaharlal Nehru Medical College, Belagavi, India.
S Yogesh KumarKLE Academy of Higher Education and Research's Jawaharlal Nehru Medical College, Belagavi, India.
Shivaprasad S GoudarKLE Academy of Higher Education and Research's Jawaharlal Nehru Medical College, Belagavi, India.
Vardendra KulkarniJJM Medical College, Davengere, India.
Sunil KumarJJM Medical College, Davengere, India.
Anna AcetuinoRTI International, Durham, North Carolina, USA.
Lindsay ParlbergRTI International, Durham, North Carolina, USA.
Elizabeth M McClureRTI International, Durham, North Carolina, USA.
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Columbia University School of Medicine, New York, New York, USA.
Jawaharlal Nehru Medical College · INRTI International · USAga Khan University · PKColumbia University · US

Funding

Bill and Melinda Gates Foundation
6 · The paper itself

Abstract

backgroundMinimally invasive tissue sampling (MITS) is a noninvasive technique used to determine the cause of deaths. Very little is known about the factors that affect MITS acceptance or refusal. We present findings from a prospective study conducted in Southeast Asia on the reasons for accepting or refusing MITS.

methodsThis substudy was conducted in India and Pakistan to determine the acceptability of MITS in women who had a stillbirth or preterm live birth who later died. A formal questionnaire was used to gather observations during the consent for MITS, such as reasons for acceptance or refusal of MITS, as well as which family members were involved in the decision process.

resultsIn Pakistan, the MITS acceptability forms were completed for 470 of 477 women (98.5%) with an eligible stillbirth for this substudy, and 334 of 337 (99.1%) with an eligible preterm neonatal death. In India, MITS acceptability forms were completed in 219 of 305 women (71.8%) with an eligible stillbirth and 260 of 264 (98.4%) with an eligible preterm neonatal death. In India, the most common reasons for MITS refusal for both stillbirths and preterm neonatal deaths were cultural concerns, while in Pakistan, the most common reason for MITS refusal was a potential delay in the funeral. The primary reason for accepting MITS was that the parents wanted to understand the cause of death. At both sites, fathers, mothers, and relatives, often in consultation, choose whether or not to accept MITS to determine the cause of death in stillbirths and preterm neonatal deaths.

conclusionsMITS was more commonly accepted in India than in Pakistan. Cultural concerns in India and funeral delays in Pakistan were common reasons for refusal. Parents from both sites were curious to know the cause of stillbirths and preterm neonatal deaths. The father, mother, and relatives were key decision makers for consenting to or declining MITS.

Indexed as

Perinatal DeathStillbirthAutopsyCause of DeathFemaleHumansInfant, NewbornMothersParentsPregnancyProspective StudiesAcceptanceMinimally invasive tissue samplingneonatal deathStillbirth

Identifiers

PMID34910175
PMCPMC8963158
OpenAlexW4200003801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.