Evidence map›Paper›PMID 34909784›Full record

ArticlemedRxiv : the preprint server for health sciences2021

Vaccinating Children Against COVID-19 is Essential Prior to the Removal of Non-Pharmaceutical Interventions.

Erik Rosenstrom, Jessica Mele, Julie Ivy, Maria Mayorga, Mehul Patel, Kristen Hassmiller Lich, Paul Delamater, Raymond Smith, Julie L Swann

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Erik RosenstromDepartment of Industrial and Systems Engineering, North Carolina State University, Raleigh, NC, United States of America.
Jessica MeleDepartment of Industrial and Systems Engineering, North Carolina State University, Raleigh, NC, United States of America.
Julie IvyDepartment of Industrial and Systems Engineering, North Carolina State University, Raleigh, NC, United States of America.
Maria MayorgaDepartment of Industrial and Systems Engineering, North Carolina State University, Raleigh, NC, United States of America.
Mehul PatelDepartment of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Kristen Hassmiller LichDepartment of Health Policy and Management, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Paul DelamaterDepartment of Geography, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Raymond SmithDepartment of Engineering, East Carolina University, Greenville, NC United States of America.
Julie L SwannDepartment of Industrial and Systems Engineering, North Carolina State University, Raleigh, NC, United States of America.
North Carolina State University · USUniversity of North Carolina at Chapel Hill · USEast Carolina University · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
Understanding the relationship between herd immunity and geographic scale to improve estimates of localized infectious disease outbreak riskK01AI151197 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DELAMATER, PAUL · 2020 to 2023
$544k
NCATS NIH HHS UL1 TR002489NIAID NIH HHS K01 AI151197
6 · The paper itself

Abstract

objectivessTo evaluate the joint impact of childhood vaccination rates and masking policies, in schools and workplaces, on community transmission and severe outcomes due to COVID-19. STUDY

designWe utilized a stochastic, agent-based simulation of North Carolina, to evaluate the impact of 24 health policy decisions on overall incidence of disease, COVID-19 related hospitalization, and mortality from July 1, 2021-July 1, 2023.

resultsUniversal mask removal in schools in January 2022 could lead to a 38.1-47%, 27.6-36.2%, and 15.9-19.7% increase in cumulative infections for ages 5-9, 10-19, and the total population, respectively, depending on the rate of vaccination of children relative to the adult population. Additionally, without increased vaccination uptake in the adult population, a 25% increase in child vaccination uptake from 50% to 75% uptake and from 75% to 100% uptake relative to the adult population, leads to a 22% and 18% or 28% and 33% decrease in peak hospitalizations in 2022 across scenarios when masks are removed either January 1st or March 8th 2022, respectively. Increasing vaccination uptake for the entire eligible population can reduce peak hospitalizations in 2022 by an average of 89% and 92% across all masking scenarios compared to the scenarios where no children are vaccinated.

conclusionsHigh vaccination uptake among both children and adults is necessary to mitigate the increase in infections from mask removal in schools and workplaces.

Identifiers

PMID34909784
PMCPMC8669851
OpenAlexW4200465600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.